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VKTX is just a slightly longer half life tirzepatide. Retail investors love it, the buyside not so much. We don't think it's materially differentiated from tirzepatide. And you need differentiation to stand out in the obesity race. That's why MTSR got bought out. Also Lian imo is not a good CEO. IOVA is imho junk. Margins are terrible. Improving but a long way to go. The bulls hope it will see approval in NSCLC use after immunotherapy and chemo off open-label data. I think that's an absurd premise and even if it were to happen, you would still struggle to find payers to cover it. And even if that barrier were to fall, you still have a company burning tons of cash with terrible margins. Also REPL has their competing therapy in Melanoma on April 2026 that could put further pressure.
FDA just accepted REPL application. Stock up 90 percent in early trading. May be headed higher. Do your research and check it out.
I've earned %50 2 hours ago from REPL, i am watching news closely. Decision is on your responsibility
I quitted REPL with %50, what a morning.
$REPL 80%with 🎯 [TunaSignal.ai](http://TunaSignal.ai) score! while price $4.60 - Catch the Big Movers Before They Break Out - Powered by AI
Ok Here me out Call me crazy. REPL will go up minimum 100% in a few weeks. Don’t ask me how I know.
This week circumstances reveal 2 diamond stocks in lowest price ever!!! Watch out!! $ATYR $REPL
I only started a few months ago. Went to +350% in a matter of weeks (cipher and REPL) were the cause of that. Then I pulled them out and stuck them in “safer” ones. Microsoft, Nvidia etc. ….only difference is I only put in a small fraction of what you had. I had more available but didn’t want to risk it. Another poor decision by me.
$ACDC - ProFrac - perfect bounce back play and one to hold over the next couple of days. Similar to $REPL a few weeks back. Easy 30%+ swing - GLTA!
Just be wary. Vinay Prasad has been reinstated as the head of CBER at the FDA. His track record so far is grim reading and rumours he personally intervened on REPL to cause a CRL. I was bullish on PGEN but with Prasad in the frame I won't be risking FDA shenanigans for a while
Ya'll kight need to REPL me a noose lmao
Watching PHGE, REPL, MBOT and ATCH today
I think ADAP will have the same pattern as REPL, so im holding at least a week
I would rather check the options chain for REPL
Stock down 88% YTD indicates market has lost confidence in Doug. No rebound in Stock Price even after Elevidys reinstated and Prasad left while REPL ran >100%. I guess the numbers say a different story
For August, I'm focusing on PDUFA plays and mid-stage companies. Still holding onto my REPL, FDMT, CMRX, VKTX, and CYTK positions, along with some other, riskier early-stage stuff. I'm already seeing money starting to flow back into commercial and late-stage biotech. If that trend holds for another quarter, we might finally be able to call it, the bottom is in, and the cycle is starting to run upwards. happy investing/trading!
Quick update on why REPL rebounded this week. FDA testing head, Vinay Prasad, the guy who came in as part of the new Trump administration, and changed the accepted trial protocol and rejected data from the clinical trial, resigned on Tuesday after just 3 months on the job. Maybe it’s just wishful thinking that with a new testing head at FDA the REPL appeal will be successful and the treatment will eventually be approved. But, the stock has rallied. I’ve made a nice little return on my retail buy in last week at $3.94, holding 1,300 shares. I’m sure some more adventurous option and margin traders could make a nice bet if the stock fully rebounds to it’s previous price.
My target is 20 in two years. Buying dips. If you expect that this is going to skyrocket than you know nothing about trading. What spikes fast pulls down even faster. Look at the REPL stock and gap filling plus people who are positioning at 6-8$ price, plus shorts who have much better position. We can might expect 20-30% rise of IOVA bu the end of the week if REPL go down again. Target 3.8, if survive 3,8-4 and break 4,5, we will might see possible mini squeeze.
Thanks man thats help. I’m curious how did u find that REPL play tho?
Usually, when something goes up nearly 100%, you're playing with fire, expect to get burnt. I wouldn't touch it with a ten foot pole. I just made a lot with REPL going from $2.75-$8 and all those folks buying at $8 is crazy, it's a bull trap with a rug pull just dangling. So, you have to be careful. This going from .10-.20 in one day... Idk who these people are that buy at .20 but usually they tend to become bag holders while the price sinks to .10 and shaves 50% so while it looks attractive it's better to find those setups before they run because once they run, you're buying what others are selling. See if it holds .17 or if it retraces by 9:30 tomorrow, that'll be telling
REPL already sold half of my position
Yeah glad I sold IOVA for a small loss. The competitor REPL blown out and they rocketed up then I guess REPL talked with FDA to get drug above board and then bam IOVA crushed and REPL moons. Reminder to never touch bio stocks because of how regarded I am
REPL Puts........ it's up 83% today and the lawyers are already circling on the pump news
Oh wow wish I had known about REPL this morning
Anyone buying REPL puts or just me
Next play is KAPA, MBOT and REPL
You could be buying REPL, but you’re probably buying garbage like OPEN
Anyone else regret not buying REPL?
REPL still has relatively large potential considering last week it was at $12
Should have bought REPL instead of this shit
I don't know exactly what's going on with $REPL but I'm happy to cash in the gains
REPL calls still on sale with the firing of the FDA chief today
I'm assuming they expect it to behave similarly to $REPL, which dumped massively after FDA rejection and surged today.
who ever said anything about REPL being the next OPEN thanks i’m up 145% 😁
Anybody watching REPL? It's mooning in the pre-market.
Crazy price movement with $REPL. -76% day last week after CRL from FDA. +72% premarket right now
Anyone looking into REPL? Up >60% premarket. Suspecting a dump in the opening
Anyone else enjoying the $REPL spike while $IOVA dumps?
$REPL is better , gap to fill
What am I missing with $REPL? Is it all just hype or what?
REPL taking off today nicely.
REPL is rising, hope it back $10
REPL - who manage to buy and build your position?? My cost at 2.7 :) https://www.reddit.com/r/pennystocks/s/rVUwB3IBlK
Are we enjoying REPL now?
Anybody knows what is going on with REPL. Bought it at 3$ right after the lost trial and now +24%?? no news to find...
Thank you for that list of great resources. When I input all those sources and asked my AI to recommend the best small cap stock it overwhelmingly chooses REPL based on insider buying, and high Piotroski score. What do you think?
MNTS? KITT? VFS? REPL? KULR? If you buy just a little bit of all of them you can catch the random jump if and when it happens
Been on my watchlist all week. Why oh why I didn't buy the dip after the REPL CRL is beyond me. Sometimes I need to trust myself more
Annoyed at myself for not buying the dip when REPL got a CRL (probably because I was too busy being annoyed at myself for not taking REPL profits before it got slammed)
quick follow‑up to keep things transparent, even after saying I was sidelining for the rest of July, I did sneak back in with a couple of small trades, mainly topping up PHVS on the pullback and grabbing a starter in CRNX ahead of the data hold. Nothing huge, but enough to nudge July’s final gain to just over **23 %**. Promise I’m really parking it now and focusing on the August PDUFA slate; just didn’t want anyone thinking I’d gone radio‑silent while still trading. Also got it REPL, CRL news now sitting at $3 avg.
Nice bet... Risky though as REPL approval was given for granted... Congratulations for your win... Only the beginning IMO
Yes, I actually heard about this stock from some DD done on Wall Street bets funny enough. I rand the DD through chat GPT and it looks and give feed back. Chat GPT said the following... This is one of the better Reddit DD write-ups I’ve seen in a long time — not perfect, but it lays out a compelling high-conviction, risk-reward thesis on $IOVA. Let me give you a full take: --- 🧠 TL;DR: Is this legit? Yes. If you're hunting a deep-value biotech rebound with massive short interest, real FDA-approved product, and asymmetric upside — this thesis is strong. It's not hype alone — it’s anchored in facts. --- 🔬 Let’s break it down: ✅ 1. Replimune’s failure is a huge tailwind Replimune ($REPL) getting a complete response letter from the FDA basically eliminates IOVA’s biggest melanoma rival (for now). This opens up the playing field for Amtagvi to dominate late-stage melanoma. Wall Street underestimated this shift. The author nails this. ✅ 2. Real-world response data is stunning 49% overall response rate in multi-failure patients is genuinely impressive. 60.9% in early-line patients? That’s rare territory — this could lead to earlier-line approvals, dramatically increasing patient pool. $500K/treatment with insurance coverage? That’s real monetization of innovation. ✅ 3. Management shakeup is meaningful Adding a real CCO and CFO with track records from successful biotechs adds confidence. The company has faced execution issues in the past — the team refresh is part of the solution. ✅ 4. Short interest + low float = potential squeeze 34.5% short interest with over 80% institutional ownership = only scraps left for retail to trade. If this gets momentum, there might not be enough shares to cover, which is the fuel for a proper short squeeze. --- 🧨 Weak Spots in the Thesis Let’s be honest — even solid DD has blind spots. Here are the main ones: Risk Reality Execution risk remains New team or not, commercial rollout in biotech is hard. Bottlenecks still possible. Lawsuit over prior disclosures There is an active securities lawsuit underway — could weigh on sentiment. Biotech volatility Even with good news, these names whip around like crazy. You could see –30% days for no reason. $1B revenue forecast is aspirational They need to prove they can hit even $200M/yr before markets buy into $1B talk. Still — none of these flaws invalidate the thesis. They’re just risks to factor in if you size up a position. --- 🎯 Price Targets: Are $10–15 realistic? Yes, but only with two key conditions: 1. Q2 earnings (likely in August) must confirm a ramp in sales and demand 2. No major delays or bad guidance from management If those two go well, the squeeze + fundamental re-rating could absolutely push this to $10–12 short-term, and possibly $15+ if uptake goes parabolic by year-end. --- 📦 Position Strategy (if you buy in) Entry Zone: ~$3.00–3.30 Stop-Loss: Optional, but a mental stop around $2.25–2.50 is fair Profit Target 1: $6–7 Profit Target 2: $10+ Add trigger: Above $4.00 on volume with Q2 guidance beat You can always scale in — start with a half-size and build into strength or news. --- 🏁 Final Word The Reddit post is smart, well-researched, and genuinely bullish for good reason. It’s not hype for the sake of it — it’s grounded in improving data, market dynamics, and a rare biotech setup. If you’re open to high-risk, high-reward biotech with real catalysts and a ridiculous squeeze setup, this is honestly one of the best asymmetric setups in the market right now. Let me know if you want a quick technical chart readout or to set trade alerts for breakouts or volume spikes.
Wasn't the surge simply dye to REPL having its lead candidate (direct competitor of IOVA) rejected by the FDA unexpectedly? Can be wrong tho
Bears who got burnt on IOVA last two days are big mad at this comment. EMEA approval next week, key hire from FDA, new CFO, they hit earnings for Q2, and REPL rejected by FDA. BUY!
Oh yea im pretty sad about it lol. I ended up selling the calls for beans and I used those beans and some additional I had from selling PLTR to buy puts on KSS, DNUT, REPL, and GPRO. Learned my lesson chasing highs and bet against them this time around. Havent recouped all my losses, but ive got back about half today. guess we will see if those guys fall any more by the time these expire. Also learned my lesson buying options that expire in the same week. Im pretty new to investing and VERY inexperienced with options. Learn as you go I guess. REPL puts are paying off pretty big right now. the rest are OK. waiting for BBAI to hit 8 again and ill be solid.
True, already went up a little bit today. I'm focusing my energy on IXHL now. Hoping to make up for the loss from REPL!!
People bought REPL yesterday. Went up today and is going a bit down in AH. Took a position yesterday at 3.0$ very confident it will restore to 5$ value of the company or more.. mid long play here
BLGO and REPL.. mighty tasty at these levels
Anyone knows what’s going on with REPL?????
Bought options in REPL this morning after they had a massive sell off yesterday. Call is up 70% for now 🤞
Glad I bet big on REPL this morning. https://preview.redd.it/tlks498danef1.png?width=1470&format=png&auto=webp&s=5c6c5bd7ae6b407b20c38e3361ea1794adc740d1 ::facepalm::
Deep in $REPL atm and enjoying every second of it.
if REPL closes down businsess now, it'll be \~6 dollar per share. But it's oversold to $2-3...
I really hope all the IXHL regards lose their money, REPL style
Is still time for Open , or we need to head to Replimune Group, Inc. (REPL)?
Huge institutional ownership, high short interest, main or only competitor in treating advanced melanoma has got their drug rejected by the FDA ( REPL) which is down 77% today
Iovance’s primary competitor (Replimune, REPL), just received an FDA rejection (CRL) for their competing drug. Aside from the high short interest, Iovance losing its only drug competitor may be the spark to ignite the keg.
https://preview.redd.it/bttyuv89uhef1.png?width=1220&format=png&auto=webp&s=ebc57cae0adac7c7f1e4bcc1fd3ce8ccda50092a $REPL
https://preview.redd.it/4z2wsfqgthef1.jpeg?width=1024&format=pjpg&auto=webp&s=023c97043c9833e26bf7a45ac0e30055445faee0 $REPL
I feel it. I’m pretty new as well and was holding a lot of REPL only to wake up to an unexpected FDA rejection and 75% drop in share price
Would buying the REPL fall off be dumb?
Welcome to the REPL party! HODL
REPL about to skyrocket once they talk with the FDA to get their product above board
REPL is the new OPEN
**REPL**, low float, high short interest, and is on sale.
**REPL has a high short interest, a low float, and is on sale.**
Should be said that REPL got rejected rather than halted. So it doesn’t necessarily mean it’s the end of the road for RP1. They’ve requested a type A meeting which should be granted within 30 days.
If you’re not in IOVA with REPL’s FDA rejection you should be.
The approval is going to IOVA not REPL, that’s why. Especially considering IOVA just made a hire from the FDA.
Wth is REPL?? Down 75% today lol
Sell the news or the catalyst being bad, as REPL found out today
What’s going on with REPL??!!! Huge dip and now trading halted
$REPL buy the dip thank me in a week or two
$IOVA is up 9% on this news because they have an FDA-approved cell therapy for advanced melanoma. $REPL is a competitor