GUTS
Fractyl Health, Inc. Common Stock
Mentions (24Hr)
0.00% Today
Reddit Posts
Mentions
GUTS still a POS. Glad I didn't buy very much. Anyone else bagholding on this one?
I’m bullish on GUTS and have a small stake.
GUTS (Fractyl Health) has been growing steadily this week.
Doe's someone has an opinion about GUTS?
I did. One of their drugs didn’t make the cut but they do have a lot In their pipeline. I’m thinking buy now and hold. I’m holding 15k shares GUTS/ 15k shares IXHL/ 3k MRKR / 5k CYN / 5k VRME / 5k CTM. In my mind, this is lost money until it’s not. Feel me? I don’t need this money for years to come so I can wait. What’s your gut on them? 50 bucks a share is super cheap. I’m just looking for a 2nd opinion
Picked up 15,000 shares of GUTS. God is great. It’s up 13% today
Get some of your tasty $DNUTs here! If you don't like your $DNUTs squeezed, go more $DRCT with low float. If you aren't down with low float, you really ought to do your $DDD... gotta remember that $DDDs are very different than $DNUTs tho... but when all the jokes suck you really should stick with your $GUTS! ;)
My guts still hurt from buying $GUTS. Bagholding now. https://preview.redd.it/ttqymckhebjg1.jpeg?width=612&format=pjpg&auto=webp&s=a4082c8cba84d1f514b0ae065fcb321fb491c85d
What are everyone’s thoughts on GUTS? I feel like it may still have a turn around, but I don’t know. I’m debating holding vs cutting my losses. I’m still pretty new to investing and am still learning! I’m
CALC and GUTS (oversold biotech) on their way up again. Bought the bottom today.
Check out this news article 👀 Fractyl Health, Inc. Investigated on Behalf of Investors - Contact the DJS Law Group to Discuss Your Rights GUTS https://www.businesswire.com/news/home/20260130967015/en/ Here's the reason why it fell down
[Here’s](https://open.substack.com/pub/biotechdistilled/p/update-fractyl-health-guts-the-mixed?r=4tawgv&utm_medium=ios&shareImageVariant=overlay) my update on GUTS given recent events.
My god people are dumb. Whether it’s OP or all the commentators. No wonder taking advice from random people on the internet is a bad idea. I’ve been following this company since last year and bought the dip at 58 cents. They have an endoscopic procedure called Revita. It’s basically shooting hot water at the duodenum. The idea being that you can target metabolic diseases and obesity. Now current state of the art treatment for obesity/weight loss involves GLP-1 (drugs like ozempic). The problem with septic is that people gain the weight back so it’s as if you need to take ozempic all the time. In comes fractal health (aka $GUTS). They promise a way to maintain weight loss after discontinuation of GLP-1 drugs. So if you’re a fat human and you take ozempic and you start seeing side effects and are like hmm how can I keep my weight down and stop ozempic then this treatment is for you. A bit about this treatment - it’s a standard endoscopy procedure and takes around 40 mins. Now onto the crash on Thursday. They released their short term study result (3 month and 45 patients across many different sites). Their results showed that compared to placebo aka sham, the treatment works but just not as efficiently as you like. The patients who didn’t get the treatment say a weight gain rate of 13ish percent while patients who got the treatment saw a weight gain rate of 4.5%. Furthermore they excluded 5 patients (from one specific facility) because they dint follow the proper lifestyle and dietary protocol required. Finally, those patients also saw a drastic reduction in cravings for dessert and stuff further bolstering this study. The difference between treated patients and placebo was statistically significant with a p-value of less than 0.05 one sided and I think p=0.07 double sided (I don’t know these numbers exactly). Basically all to say that in the eyes of fractyl and most scientists/doctors this was a very successful study with really good results. What investors didn’t like were two things: (1) the 4.5% Regan (they wanted that number to be around 1.5% and (2) the pathway to FDA approval (PMA vs De novo). PMA is slightly better for more complex procedures while de novo is more in fractyl’s reach. Either way - the product should have no problem getting into FDA’s approval pipeline. Now fractyl will do a 6 month study starting g February and depending on those results they’ll apply for FDA approval. So far their results show that the procedure works and FDA will give them green light. I’m not sure why the fuck the stick dropped. I was not invested in the stock when it tanked but I bought in because I couldn’t pass on this opportunity. This is a 200 million market cap company at least (1.x dollar price). With better FDA results the price should be more like 3-4 USD. Read the 8-k they released on January 29th or go to their website and listen to the seminar. The 8-k also has a 99.2 document that has all these results. Ok hope this helps!
JTAI probably for a swing, but GUTS for a recovery? have you read up on the most recent news about GUTS, it's literally in the gutter, Morgan Stanley downgrade has finished what's left of it, i'd be shocked if it recovers.
GUTS dropped hard because several negatives hit at the same time. The midpoint data from the REMAIN-1 study was weaker than what the market had priced in: results were framed as positive, but the actual effect on weight regain after stopping GLP-1s was only moderate and not statistically powered for strong efficacy claims. On top of that, management signaled a change in the FDA regulatory path for Revita, creating uncertainty around approval timing and risk. At the same time, news about a securities law investigation added further pressure. Since GUTS is a pre-revenue clinical biotech with high cash burn and a small market cap, sentiment flipped quickly and the stock sold off aggressively. So yea many factors came into play for that price action lol
GUTS for a recovery play, JTAI for swings
Fractyl Health, Inc. Investigated on Behalf of Investors - Contact the DJS Law Group to Discuss Your Rights GUTS https://www.businesswire.com/news/home/20260130967015/en/
My Guts is telling me GUTS is gonna start doing good, but no fr, I invested a few bucks and it’s only going up, so I’m pretty satisfied ☺️
Feeling sick to my GUTS after buying some $GUTS.
What the hell happened to GUTS
Holding GUTS for a bit, fingers crossed. Did nothing today. Maybe a rebound tomorrow?
No GUTS no glory. I'm I'm for a potential rebound 🙌
Whats the GUTS play, I'm unfamiliar?
Yesterday biotech CALC crashed and bounced huge. Last week it was biotech IOBT. Will GUTS bounce huge today or tomorrow? https://preview.redd.it/d6dab3mzhbgg1.png?width=158&format=png&auto=webp&s=665f372c837ad0b57acff7a9a6a08d8c5c4a63c1
Who has the guts to play a GUTS bounce? Elmos guts: https://preview.redd.it/3imx8ykiebgg1.png?width=115&format=png&auto=webp&s=9038765cb8e9f34125b8b650876bac1efbcb9079
Still thinking GUTS will bounce big sometime today or tomorrow.
GUTS cmon pull a CALC!
A big bounce on GUTS is likely.
Do we know why GUTS crashed recently ?
GUTS, GTSC, SGMT, bought the dip on all of them. Let's see what they can do!
Who even knew there was a ticker called GUTS
RIP to the man who posted calls about GUTS yesterday... Damn stock market
I'm buying GUTS at $0.68. Seems like a harsher reaction than it should be. Hoping to catch a rebound to $1.
Hey oversold biotech guy, you buying GUTS?
This ticker should be sued for name manipulation. How can people resist having GUTS!
What is GUTS? What is this fucking chart? This looks horrible. Why is it going up Friday?
Couldn't post from my investing account cuz it's recently made but this is why I'm banking on this stock: $GUTS 6-month REMAIN-1 midpoint results out by the end of the week! This is the kind of clinical data that would turn fractyl health's already promising findings into real and durable results that investors can get behind, with analysts predicting a **300-500%** upside. This might be a biotech **What is Fractyl Health trying to do?** For people unfamiliar with Fractyl Health, they are currently researching Revita, an endoscopic procedure that gently resurfaces the mucosal lining of your small intestine to increase insulin sensitivity, blood sugar control, and appetite regulation. People with diabetes and obesity develop metabolic patterns in these cells. The mucosal lining secretes hormones that make maintaining weight after weight loss difficult. After 1 year of stopping GLP-1 medications, many people regain 30-50% of the weight they lost. Revita helps lock in weight loss after stopping GLP-1 medications. Not only does it cost $1000-1350 a month to stay on these medications. Nobody wants to feel like they have to stay on a pill their whole life to keep weight loss they have pain-stakingly earned. **CLINICAL DATA:** - Fractyl health's randomized 3-month REMAIN trial data showed the sham group regaining 10% BW - People who got revita continuing to lose 2.5% of BW, even after stopping GLP-1's. - Their open label REVEAL-1 cohort 6 month data shows a mean weight gain of 1.5% BW as opposed to the usual 10% people regain after stopping GLP-1s. **THE UPSIDE:** The GLP-1 market is currently estimated to be $50-65 billion in 2025, with forecasts that it could even rise to 210 billion by 2035. Personally working in healthcare, seeing the increasing prevalence of GLP-1 drugs and understanding the risk of similar endoscopic procedures (<2% of serious complications, patients are home the same day), I have a strong conviction that if results come through, PDA approval and consumer adoption is almost guaranteed to follow. With interest from investors like Peter thiel and Alphabet who already have a stake in GUTS, I'm excited to see how investors move once this stock becomes significantly derisked
Any news on GUTS today? I am long it. I know some data expected to be released soon. My other two holdings are PCT and AUR.
ya'll like fuckin DRAGONS? https://seeders.github.io/GUTS/projects/BoidSimulation/index.html
ALT and GUTS serves two different customer base in the weight loss market mate
Core Differences • Business model: $GUTS builds and commercializes therapies; $LEXX builds a delivery platform for licensing/partners. • Stage of development: $GUTS is in pivotal, device-oriented clinical progression; $LEXX is in early clinical and discovery/optimization phase.  • Market positioning: $GUTS targets a concrete therapeutic niche (post-GLP-1 weight rebound), while $LEXX targets broad pharmaceutical delivery opportunities across multiple APIs.  • Risk profile: $GUTS is still early but further along operationally and with broader analyst coverage, while $LEXX is higher risk with a smaller footprint and more dependency on partnerships. ⸻ Bottom Line • $GUTS is a metabolic device/therapy company with ongoing clinical catalysts and clear regulatory milestones.  • $LEXX is a micro-cap biotech platform company with a unique delivery technology and early human validation, but far more speculative and partnership-dependent.  They both play in the broad metabolic/health innovation space, but their paths, risks, and investor profiles are very different.
The main issues with a lot of GLP-1 treatment is that we do not know long-term side effects and that once you are off, you gain your weight back. I like how $GUTS addresses these issues and I think it is the next big thing in this space. My dd can be read [here ](https://www.reddit.com/r/pennystocks/comments/1q0bced/why_guts_and_achv_are_my_top_biotech_picks_for/)and [here ](https://www.reddit.com/r/pennystocks/comments/1p0803b/why_i_feel_that_fractyl_health_guts_is_the_most/)for those interested.
GUTS Fat goes down when $GUTS goes up!
If you’re buying GUTS then you have to buy GLRY as well
Its sad but not tragic.. and its not yet the end of the world. Believe me I am in your shoes a year ago. Now i am slowly fighting back and recovering. I want to offer you a RED and a BLUE. If you decide to take the RED pill visit my website [www.reneyagahon.com](http://www.reneyagahon.com) sign up and see where the rabbit hole goes. But if you think you're only a guy with no GUTS and PURPOSE to fight back then take the BLUE pill and wake up the next day on the same miserable situation. Whether you are crazy or not, your life is still in your hands and nobody else. Believe me, YOU WILL THANK ME IN THE YEARS TO COME! See you in the rabbit hole! [WWW.RENEYAGAHON.COM](http://WWW.RENEYAGAHON.COM)
Interesting. I've been looking at GUTS recently. Not the same but in the same general field. I'll be watching this one though. Thx
Interesting. I've been looking at GUTS recently. Not the same but in the same general field. I'll be watching this one though. Thx
Just did some research on this stock and I like what I'm seeing! Not sure of a price target, but analysts think $7 eoy next year. Based on positive results on new weight-loss drug, patents and funding received, GUTS seems bullish heading into 2026. Thanks for the tip!
Why do you like GUTS?
GUTS is climbing hard. Thinking of adding more
Looking only at price/news history, GUTS is set up for a rug pull
What this chart tells me is that $GUTS has rejected any movement above 200dma. Shorts it is.
https://preview.redd.it/4fc4b05rd12g1.png?width=699&format=png&auto=webp&s=07d2384d650cf2b0ec32ed03a0371e7baae71547 Patent received for $GUTS
Holding: MBOT AMC Watching: VVR ALLR GUTS IPW JZXN HRTX
Im balls deep in GUTS right now. Super undervalued stock imo. They are doing clinical trials right now things are looking successful. Anyone else in ?
Guess who owns a part of GUTS by a lot of time. Thiel.
$NVO $LLY shaking after $GUTS recent trial results!!
$GUTS gonna continue mooning!! Don't miss it!!!
💥 GUTS vs GLP-1: The Biotech Underdog with a Shot at the Throne 💥 Everyone’s chasing GLP-1s — Ozempic, Wegovy, Mounjaro — trillion-dollar dreams, obesity wars, insulin disruption. But while the giants fight over injectables, Fractyl Health (GUTS) is quietly building a procedural revolution. 😂😂 #13 highest gainer today.
Clearly, you didn’t read and do actual research on what they are doing 💥 GUTS vs GLP-1: The Biotech Underdog with a Shot at the Throne 💥 Everyone’s chasing GLP-1s — Ozempic, Wegovy, Mounjaro — trillion-dollar dreams, obesity wars, insulin disruption. But while the giants fight over injectables, Fractyl Health (GUTS) is quietly building a procedural revolution. HODLYourGUTS
💥 GUTS vs GLP-1: The Biotech Underdog with a Shot at the Throne 💥 Everyone’s chasing GLP-1s — Ozempic, Wegovy, Mounjaro — trillion-dollar dreams, obesity wars, insulin disruption. But while the giants fight over injectables, Fractyl Health (GUTS) is quietly building a procedural revolution. #HODLYourGUTS
💥 GUTS vs GLP-1: The Biotech Underdog with a Shot at the Throne 💥 Everyone’s chasing GLP-1s — Ozempic, Wegovy, Mounjaro — trillion-dollar dreams, obesity wars, insulin disruption. But while the giants fight over injectables, Fractyl Health (GUTS) is quietly building a procedural revolution. #HODLYourGUTS
GUTS https://preview.redd.it/qds99pxoomrf1.jpeg?width=1170&format=pjpg&auto=webp&s=7cf9b63652e2a4abbb621c621f830716d150cd90 # HODLYourGuts Let’s start a movement
# GUTS Lucky no. 13 in Gainers today! And the ride will be wild til Oct 3rd and 1Q 2026 https://preview.redd.it/3q8xpm7qmmrf1.jpeg?width=1170&format=pjpg&auto=webp&s=4dd01fa7e4ce6e92ee5e6efe60a31b97dbcc4684
GUTS, GPUS, DFLI, I'm still holding AIRE as well. RR is also a good buy. I'm also holding Pharma positions in CGTX, SANA, and ELDN because of what they do.
GUTS$ is literally living up to the ticker. +29% today after dropping a $60M offering at $1.00. Diamond hands only—this is biotech roulette with a side of metabolic moon juice. They said obesity + diabetes are “too big to cure.” Fractyl said: hold my pancreas. 🩸💉 Not financial advice, just vibes.
GUTS is very similar to NMRA. Look what happened to NMRA when their trial drug failed.
check out GUTS. obesity treatment where patients kept losing weight AFTER they finished GLP-1 (like ozempic)!!!!!! hedgies trying to keep the price down cause of warrants!!! NO $GUTS NO GLORY!!!
Show your guts and buy GUTS
anyone hear about $GUTS??? released amazing data but funds are trying to keep it down. stock price will fly if it passes 1.37 https://preview.redd.it/8sjnuqdy4jrf1.png?width=1930&format=png&auto=webp&s=a839be093cac37a91e7d87ef9f359db8c85c1c01
CGTX , SANA, ELDN, GUTS, MBOT OPEN , IXHL, DNUT, AIRE Do you're own research and deductions and as always trade at your own risk and trade responsibly 🤙
Make it a GUTS by buying puts expiring this week
Yeah, i’m pretty positive that melania HATES THE ORANGE TURDS GUTS!!! i donʻt think i’ve ever seen her smile, once. Except for just now, in the report about melania sueing hunter for 1 billion. the picture of trump, epstein, Ghislaine and melania. melania is smiling like she’s having the time of her life. She looks to be about 12 years old.
GUTS might make a small rebound in the morning. Who's in?
GUTS has some suspicious movement going on after hours
Risky bet, but if Revita data lands, $GUTS could rip. Peter Thiel backing and post‑GLP‑1 angle make it spicy.. lottery ticket vibes.
Much prefer RXRX, PDSB, VOR, GUTS
$GUTS is looking good today. Might make it over $2.
Don't take its $GUTS out just yet! This might be an overlooked opportunity right now as Peter Thiel is in at $15, stock trades at $1.78 (as of July 18, 2025) and GLP-1 patents are expiring Here’s why it caught my attention: • Peter Thiel and Mithril Capital first backed Fractyl way back in 2014 in a $40 million Series C round. That’s a 10-year hold already—far from a quick flip. Source: https://www.reuters.com/article/markets/mithril-capital-leads-40-million-financing-in-fractyl-labs-idUSL3N0R51MF/ • He doubled down at IPO, buying public shares at about $15 per share in early 2024. That puts his cost basis around $15, while the stock is now trading closer to $1.70. That is either a huge misread or an incredible mispricing. Source: https://www.sec.gov/Archives/edgar/data/1572616/000119312524257370/d863183dsc13g.htm • The current market cap is only about $87 million. If this company can prove its concept, even a modest recovery toward $1 billion valuation delivers 10x returns from here. That’s not hype, it’s math. • Mithril hasn’t dumped shares. No insider selling, and Thiel hasn’t exited. That tells me the smart money still believes in the story, quietly. As the line goes from Wolf of Wall Street: “Don’t judge me by my winners, judge me by my losers, because there are so few.” That’s exactly how I see it when I look at Peter Thiel’s past picks like Meta, Palantir, and others. He doesn’t swing often, but when he does, it usually counts. TL;DR: Peter Thiel owns $15/share in $GUTS, now trading at $1.70. Still holding. Market cap is tiny, tech is FDA-backed, and competition (Ozempic) has patents expiring soon. Could this be another Palantir-like sleeper? Maybe. Worth a look Not a financial advisor
$GUTS might be an overlooked opportunity right now—Thiel is in at $15, stock trades at $1.70, and GLP-1 patents are expiring • Peter Thiel and Mithril Capital first backed Fractyl way back in 2014 in a $40 million Series C round. That’s a 10-year hold already—far from a quick flip. 📎 Source: https://www.reuters.com/article/markets/mithril-capital-leads-40-million-financing-in-fractyl-labs-idUSL3N0R51MF/ • He doubled down at IPO, buying public shares at about $15 per share in early 2024. That puts his cost basis around $15, while the stock is now trading closer to $1.70. That is either a huge misread or an incredible mispricing. 📎 Source: https://www.sec.gov/Archives/edgar/data/1572616/000119312524257370/d863183dsc13g.htm • The current market cap is only about $90 million. If this company can prove its concept, even a modest recovery toward $1 billion valuation delivers 10x returns from here. That’s not hype—it’s math. • Mithril hasn’t dumped shares. No insider selling, and Thiel hasn’t exited. That tells me the smart money still believes in the story, quietly. TL;DR: Peter Thiel owns $15/share in $GUTS, now trading at $1.70. Still holding. Market cap is tiny, tech is FDA-backed, and competition (Ozempic) has patents expiring soon. Could this be another Palantir-like sleeper? Maybe. Worth a look.
# $GUTS - NEWS Fractyl just dropped new data that could shake up obesity and diabetes treatment. Their gene therapy, **Rejuva**, showed in mice: * **20% weight loss** * **38% drop in blood sugar** * Lasting effects after **one dose** * No safety red flags It only activates when needed, targeting the pancreas without constant drug exposure.