CRSP

nsd433

CRSP rules are here: [https://www.crsp.org/wp-content/uploads/guides/CRSP\_Market\_Indexes\_Methodology\_Guide.pdf](https://www.crsp.org/wp-content/uploads/guides/CRSP_Market_Indexes_Methodology_Guide.pdf) Page 11 deals with new securities (aka IPOs). The default is to wait 20 days and 12.5% float. But there's a "fast-track" whereby it can be 5 days and 10% float. I can't find the rules which govern whether a new security gets fast-tracked.

SirGlass

Yes , this already happens with the CRSP US Total Market Index I believe

SirGlass

This isn't going to affect VTSAX , VTSAX does not follow the nasdaq 100 index, it follows the CRSP US Total Market Index. I really doubt the CRSP indexes will change their rules

runnerofshadows

Might become VTI or VT and chill - I know VTI uses CRSP not S&P or Nasdaq and VT uses FTSE Global All Cap Index. There's also VXUS if you want a dash of International exposure.

Thuradzon

Vanguard follows S&P 500 Index & the CRSP index. I wonder if they would change their rules too.

ScarfingGreenies

My last search said they both were considering it as well. Vanguard's VTI follows CRSP and as of now they're not considering a rule change. They do have a fast-track rule but SpaceX doesn't meet it since they're only offering 5% float and CRSP requires at least 10%. Not sure what OpenAI and Anthropic are offering float wise.

Kemilio

Sell indices. Buy blue chip and personal favorite stocks that have tanked for the long term (MSFT, UNH, CRSP, SATL, MU). Buy calls on volatile stocks/futures/leverages for some short term fun (GUSH).

Loose_Stool_12

😮 No idea. But that's 1 of only 2 health stocks I own in my Roth. (Other is CRSP) What am I missing?

kiwimancy

>I appreciate the skepticism, but there’s a misunderstanding here about index mechanics. The misunderstanding is yours. >If Nasdaq creates a 'Fast Entry' express lane for a trillion-dollar IPO, it forces broad-market index providers (like CRSP and S&P) to accelerate their own inclusion dates to avoid 'tracking error.' That is simply false. CRSP and S&P are free to construct their indexes however they want. Tracking error is not applicable in this context. >While the prospectus mentions 80%, Vanguard and BlackRock managers are strictly measured by how perfectly they track the index. Right, and only the Nasdaq indexes would include the IPO. >All technical citations regarding SEC Release No. 34-104968 and Rule SR-NASDAQ-2026-004 have been manually verified for accuracy. What does "manually verified" mean? Your links to SEC Release No. 34-104968 and Rule SR-NASDAQ-2026-004 are **made the fuck up**. They have nothing to do with Nasdaq's intention to include companies in their index earlier after a large IPO. That proposal is about a continued listing requirement for small companies.

wicked_wildflower

I appreciate the skepticism, but there’s a misunderstanding here about index mechanics. 1. Index Agnostic: Funds like VTI and VOO track the entire US market, including stocks listed on Nasdaq. If Nasdaq creates a 'Fast Entry' express lane for a trillion-dollar IPO, it forces broad-market index providers (like CRSP and S&P) to accelerate their own inclusion dates to avoid 'tracking error.' 2. Leeway vs. Math: While the prospectus mentions 80%, Vanguard and BlackRock managers are strictly measured by how perfectly they track the index. They can't just 'opt-out' of a $100B+ inclusion without their fund failing its primary mission. My concern isn't clickbait; it’s about forced volatility. When the 'Fast Entry' rule waives seasoning, it forces every broad-market index fund to buy during the Day 15 hype peak, rather than waiting for a stable price floor. The reason I’m posting this information is because several people across several forums are mentioning it. People are either in disbelief or feel there is nothing we can do. I asked Gemini if there was anything the average index fund investor could do and this information was presented. I appreciate collaboration with others who are more familiar with any or all of the legalities. --- Transparency Note: Research and drafting for this post were assisted by Gemini 3 Flash (March 2026 version). All technical citations regarding SEC Release No. 34-104968 and Rule SR-NASDAQ-2026-004 have been manually verified for accuracy. Final analysis and conclusions are the sole responsibility of the human author.

Valvador

VTI tracks the CRSP index, which is a few thousand companies. I posted about it [here.](https://www.reddit.com/r/investing/comments/1ru1gw4/why_the_spacex_ipo_should_be_concerning_to/oailxls/) But yeah, based on that after about 20 days on Market it would be included in VTI.

TMooAKASC2

Also CRSP isn't changing any rules, right? The float will be properly weighted?

Valvador

I think it must just be the [CRSP US Total Market index.](https://www.crsp.org/wp-content/uploads/guides/CRSP_Market_Indexes_Methodology_Guide.pdf) > ADD THRESHOLDS > An uninvestable security that has subsequently passed all of the investability drop screens for four consecutive rankings (now considered for reinclusion) must also pass the more restrictive add thresholds before it can be readmitted (added back) to the CRSP Market Indexes. > • Market capitalization ≥ $15 million > • Float ≥ 12.5 percent > • Sparse trading score ≥ .001 > • Consecutive days of zero volume < 10 > • Not currently suspended

Kemilio

We’re dropping, but I’m DCA’ing into MSFT, CRSP and my moonshot SATL. Also dipping into crypto ETHs as well.

iccreek

I honestly don't even care if this is a scam, whether you're a salesman or not i gotta admit you caught my stoned attention, i still understand nothing and won't get into the topic of graphene stocks as I'm poor as shit and my $27 in CRSP is down 13%. What I'm getting at is It was an entertaining read, thank you

casual_yak

Turns out Beam is down 63% over the last 5 years and CRSP is down 48%. Congrats, you both lose!

cosmicmeander

CRSP director did this in June last year (around $50m) and the share price went from around $40 to $80 in the space of a few months

Complex_Aardvark_661

This is the kind of post everyone should see before they get too confident about their stock picks. I've done similar lookbacks on my own "conviction" ideas from a few years ago and the hit rate is embarrassingly low. The thing that stands out to me is that the actual 10x winners (VRT, SMCI, NVDA) weren't the ones people were hyping. They were mostly boring infrastructure plays that got pulled into a megatrend nobody fully saw coming. Meanwhile the "obvious" picks like BYND and CRSP had great narratives but the fundamentals never backed up the valuation. I think the honest takeaway isn't just "nobody knows" but specifically that narrative-driven picks have a way worse hit rate than fundamentals-driven ones. The companies that actually 10x'd had real revenue growth and expanding margins, not just a compelling story. Curious what process people use to actually separate the signal from the noise when researching stocks, because everything feels like a great narrative when you're buying.

prodigyya

CRSP needs more love, they are actually doing great things. Bring back 2021 damn it.

SteveStacks

Can CRSP hold it together?

StophJS

Considered splitting my Amazon position and buying CRSP this morning before it took off lol

Mobile-Bar7732

It's just ok. If president pu55y grabber didn't start a trade war it would have been a lot better. Obama had the 2nd best returns under any president. Biden didn't do too bad in 2024. [S&P 500 Performance by President](https://www.macrotrends.net/2482/sp500-performance-by-president) 2024 Returns - Dow Jones Industrial Average 12.88% - S&P 500 Index 25.02% - CRSP US Total Market Index 25.81%

Hurricane_Ivan

>2025 Returns - Dow Jones Industrial Average, 14.9% - S&P 500 Index, 17.9% - CRSP US Total Market Index 17.10% That's some pretty serious winning. I'm buying the dip(s)

Mobile-Bar7732

Considering the DOW is only about 30 stocks the S&P 500 or the CRSP US Total Market Index would better represent the entire US market better than the DOW. 2025 Returns - Dow Jones Industrial Average, 14.9% - S&P 500 Index, 17.9% - CRSP US Total Market Index 17.10% Also, saying the DOW hit 50,000 means nothing. If someone asked how well your car performs would tell them it has 50,000 miles on it?

prodigyya

CRSP

davideeng

Hey! Sorry I’m late to this thread, but I just wanted to add I have almost an identical portfolio to you : RKLB instead of ASTS, NBIS, CRSP, BULL instead of HOOD, and for nuclear energy part, was debating between TLN or VST instead of SMR. What are your thoughts on those 2 (TLN and VST)

Thin_Cat8817

"the FDA is shifting its default policy to require only **one** adequate and well-controlled clinical study for new drug approvals, dropping the long-standing two-study standard." Lowkey biotech might be the play here. has recovered some but still pretty damn cheap since agent orange took office. Lot of room to run up potentially I like IOVA and CRSP but XBI is the easy bet

The_Last_Otter

One day CRSP will come through, hopefully AI can help accelerate their research. But I’m with you about Healthcare, such a boring slow growth sector. I’d probably do a 60%GEV/30%GE/10% GEHV split or something like that. Definitely grabbing GE before GEHC though!

Fit_Square_520

Funny..I have a small chunk of CRSP too..down 20% from when I purchased a few months back..but agree that it has moonshot potential. Healthcare just feels like a crapshoot but GE seems to know how to execute and the name to back it up. I'll be continuing to watch it and probably jump in at some point when the time seems right. Its pretty reasonably priced.

The_Last_Otter

I literally have no exposure to Healthcare besides CRSP… which is basically just a small moonshot position. Looking for one a little more established but also on the “growth” side. The GE’s kinda seem like a holy trinity

throwaway2676

Yup, I've started going into gene therapy (e.g., CRSP, BEAM) and antibody/peptide design companies (e.g., ABSI, ABCL, GMAB) myself

TheNewOP

I dislike target date funds. If you're okay with slightly more risk for more return on average, see if they have a low expense ratio S&P 500 or CRSP index. Honestly since you're holding until retirement the risk added is marginal.

Working-Country2156

Any news on buy out for CRSP?

ExPatBadger

Thank you, this CRSP index was exactly what I was imagining. Thanks for the lead.

Successful-Tea-5733

Yes, but it seems odd that the "CRSP US Large Cap Growth Index" with more holdings would be more top heavy. That's what I'm really trying to understand.

Successful-Post-4023

They track different index’s why would they be the same? From the Vanguard website: “VUG seeks to track the performance of the CRSP US Large Cap Growth Index”. QQQM is the top 100 stocks in the NASDAQ.

ATypingDog

Vanguard Institutional Total Stock Market Index is close enough to VOO that you shouldn't worry about the difference. It and VTI both "seek to track the performance of the CRSP US Total Market Index."

HereGoesNothing69

CRSP US Total Market Index uses free float market capitalization. If they IPO at $1T and only 5% of the shares are trading, they'd be weighed as is they were $50B companies.

hank_moody_madafaka

CRSP US has a total market cap of $64 trillion, so $1T would be 1.5%, which is less than yesterday's max drawdown

Mundane-Charge-1900

First of all, they do not "have to buy on Day 1". It takes times for indexes to adjust. Moreover, indexes like S&P 500 have profitability requirements for any stocks they hold. They must be profitable in the previous quarter and profitable over the sum of the last 4 quarters. Because of this, they can't even enter the index for at least year after IPO. Even VTI's index CRSP US Total Market Index only reconstitutes quarterly, and has rules for who can be included. Beyond that, you could argue that it's all priced in anyways.

tribbans95

No dude.. CRSP US Total Market also have eligibility rules. Must trade for at least 4 trading days before they are eligible for "Fast-Track" inclusion. Also even if SpaceX IPOed at a massive $500 billion valuation, it would only represent about 1% of a total market fund like VTI. You’re right about being exit liquidity though. The VCs made their money and are selling it to the public and you missed the 100x growth in the private sector.

Veloder

It doesn't mean the funds tracking the CRSP have to add it immediately, only at the next quarterly rebalance. Even if the IPO company times it perfectly to go public shortly before the rebalance, there will be at least some days the company will be public before being added to the total US market funds (probably enough to be dumped if the market decides it).

TraditionalMango58

You're thinking of the S&P 500. Total Market funds (VTI) are different. VTI tracks the CRSP US Total Market Index. CRSP has a 'Fast Entry' rule specifically for massive IPOs. If a company is big enough to qualify for the Large Cap basket (which a $1T OpenAI obviously would), CRSP adds it to the index within 5 trading days

TraditionalMango58

You're thinking of the S&P 500. Total Market funds (VTI) are different. VTI tracks the CRSP US Total Market Index. CRSP has a 'Fast Entry' rule specifically for massive IPOs. If a company is big enough to qualify for the Large Cap basket (which a $1T OpenAI obviously would), CRSP adds it to the index within 5 trading days

Ok_Cry7572

Here is how Cathie Woods largest holdings performed in January 2026 Tesla $TSLA -4.3%🔴 Crispr $CRSP -4.7%🔴 $ROKU -12.3%🔴 Tempus AI $TEM +1.3%🟢 Coinbase $COIN -13.9%🔴 Shopify $SHOP -18.5%🔴 $AMD +10.5%🟢 Robinhood $HOOD -12%🔴 $BEAM -0.3%🔴 Teradyne $TER +24.5%🟢

dvdmovie1

I like investing in biotech, have never invested in EDIT (or CRSP, NTLA are other ARKG-ish names that have often come up.) "biotech winter" There's a lot of things that have done well. XBI actually had a good year last year. " if literally anything goes right (data, partnership, asset sale, etc) the stock could reprice hard." True, but at $2, you have to take into account that a lot EDIT-specific has not gone right, it isn't just the sector. This isn't down 97% since late 2021 because of factors beyond the company.

composer98

5 years ago, Cathy Wood, right? CRSP has done nothing since her great promotion.

ServerTechie

I got tired of researching and babysitting individual stocks. I’m entirely ETFs with the exception of AAPL shares I’ve owned for many years, and some shares of CRSP as a gamble.

generatedusernames1

Glad to hear it’s 1/3 of portfolio (unlike this subs tendency to “yolo” full accounts), but man idk about CRSP. Wishing the best for you though! Ps. I do not trust Cathie Wood and neither should anyone based on some hilariously uninformed statements she’s made in the past

PalpitationSmooth992

the only hope for CRSP is to get acquired ive been bullish on the technology since it existed but look at their revenue and their market cap one single draw down on the market will bring this back to 30 im a buyer under 50 but not above

Cl0wnbby

CRSP and NTLA are have the biggest potential in gene editing.

Scared_Step4051

They definitely don’t “have all the patents.” The core CRISPR IP is owned by universities and licensed across the industry, including by CRSP. They do have strong patents around their specific therapies, but they still pay royalties like everyone else. They’re early on approvals v competition, but that doesn’t magically short-circuit reimbursement, manufacturing, or timelines to meaningful revenue.

M4chsi

I think CRSP has all the patents, they were the first ones, and I believe they are the first ones to provide approved therapies. The question is really, when will the market realise the impact and future value? Currently they believe in AI.

Bits-n-Byte

I'm a little heavy into CRSP as well but not ready to full port. Bio tech and bio engineering definitely has a future wave but not sure which company will be king.

Snoo-90587

What’s the news on CRSP

Kemilio

My money is on CRSP. Current leader in gene editing with a long runway of cash burn. But I’ll admit right now im flipping it. I buy when it’s low, sell when it’s high. Long term I think it’s a winner, but whether itll hit big time in 2 years or 20 years i have no idea.

PrimaryRepulsive

not a big investing guru😂 Plan stays the same... Consistant VWCE, ISOE and then handpicking some bonbons😅example: TEVA, SLB, CRSP, OKLO, TM and so on... (mostly smaller amounts just to have a position and see where things are going) +crypto +silver/gold

phishbo

I found CRSP from a YouTube short about mapping genes. Had nothing to do with the stock.

ballimir37

Goog VTI CRSP 35%

TannerBeyer

CRSP Leading gene editing company.

Technical-Visit-9447

What is up with CRSP today? Up almost 10%

bawireman

CRSP

Revfunky

I rarely hold a stock that long. Most people don’t hold a stock that long. We can’t prognosticate that far into the future. More importantly, what is your exit strategy? Without a strategy you are just a seal swimming amongst the sharks. Will you freak out if one stocks drops 50%? I already know the answer yet it begs the question. Are you doing any Fundamental Analysis? Technical Analysis? I don’t care for your picks, no disrespect. Your question is more complicated than you may think. I will play my part lest it be said I’m a curmudgeon. BRKB- buy the dips EQR- buy the dips CTRE COPY- buy the dips ABBV PSHZF CRSP- buy the dips until 2030 MKL This is what I have that I could reasonably conceive one may own ten years from now. I added CRSP for future potential rather than Fundamental or TA. Not my best work but what can you expect for free.

Away-Patience8556

CRSP $60 April 17 C

i_dont_like_turnips

My biggest bagger was CRSP. I found it when their technology and published papers started showing up almost weekly on a podcast I enjoy (This Week in Science). I believed in their technology because the science showed CLEARLY that it had incredible possibilities. Then their founders won nobel prizes for the tech, and they got bought into by ARK and the loonies who follow Cathie Woods. Honestly I would say to just think and keep your eyes open. You never know where a little common sense can reveal a gem. Like, walk into Costco and look at the line stretching all the way around the store, without an open parking space in the lot. And it's like that all the time. With the right eyes you'd look at that and say "there's something here."

jhvuca

u/Prudent-Corgi3793 thanks for sharing the dataset on the index returns against other assets. Would be interesting to see the breakdown of each index and how much of the top constituents drove the majority of the returns. for e.g. Mag 7 driving like 30-40% of the returns for the S&P and perhaps an even larger portion of the QQQ or the Nasdaq 100. Would you happen to have that dataset? Especially for the CRSP Indexes?

NextTime2020

CRSP

parvicus

CRSP

stockman313

How are people feeling about CRSP?

Sauce_Chucker69

CRSP

No-Atmosphere-2528

I'm in on RIVN and CRSP, though I think CRSP might pull back to the 30s before taking off (it's also a long play so beyond 2026; they both are really).

kaniyajo

CRSP

Revfunky

Nothing wrong with taking moonshots. It behooves oneself to adhere to proper asset allocation and utilize a trailing stop. You can’t win the game if you don’t risk meaningful stakes. I am of the mindset older investors should still take risk with the proper parameters in place i.e. a 4% asset allocation with a 25% trailing stop. I have one portfolio that I swing trade speculative stocks. We call them “pop stocks”. That portfolio averaged 85% this year. I buy the dips and sell the dips. Wash, rinse, repeat. I am invested in CRSP, not for fundamentals but for the technology behind it. One news article could send the stock flying. This I would consider a moonshot stock. Majority of my holdings are in safe, long term plays that generate income. I do have a space in the portfolio for ten-baggers as well. It takes patience to get a ten-bagger.

justaskthe_axis

I think PLTR has another run in 2026 before it pulls back. I like Biotech stocks like CRSP to do well and MSTR and AMZN to also out perform. Defense sector as well.

Professional_Help_85

Surprised no one mentioned CRISPR stocks like CRSP NTLA CRBU

Secret_Illustrator88

CRSP

Mattreddit760

Still waiting for my precious CRSP to do something

Revfunky

CRSP. This one is in my ten-bagger portfolio. I also swing trade the dips. This is one of the few times where I am buying based off of the potential of the stock and not fundamentals. I think it could be a household name in five years. They have already cured one disease. Not treat, cure. CRSPR stands for clustered regularly interspaced short palindromic repeats, which forms the foundation for genome-editing technology. CRSPR won the Nobel prize in chemistry in 2011. CEO Sam Kulkami expects in five years to have up to 30 different programs in the clinic. This is a speculative investment. The investment is in the platform- and its tremendous potential- not current sales and earnings. Always use proper asset allocation (I use 4%). In the ten-bagger portfolio there are no trailing stops due to the volatility. Buy the dips until 2030 is the strategy I am using.

No_Cell6708

It's almost funny to see it up there with the others. I find it odd that I don't hear about the Russell as much, though I don't live in the U.S. If I turn on Bloomberg or something, it's always the Dow, S&P500, and Nasdaq that are displayed on screen at all times. The big US total market ETFs seem to be based on the CRSP US total market index, so it doesn't show up there either.

Infamous-Office7469

CRSP. Bought a load of it when I was a noob and have been down anywhere between 70-40% for the past several years lol

YogurtWorking9246

MESO, CRSP, LPTX all potential biotech acquisition targets.

Professional_Help_85

What is all this CRSP buyout talk? Anyone know the source?

ProfessionalSite1298

Get in $CRSP before it’s too late

just-one-jay

I’m not throwing shade, I’m just saying my investing theory. Morally/academically I think the guy is a grade a loser; that’s however not part of my prospectus here. I see great value in PFE, GSK, MRNA and CRSP. And I don’t mean anything below to be political beyond its functional importance to my investing strategy. Who were the loudest people against the COVID vax? Republicans Who were the first people to get concierge COVID vaxs rushed out to them under Donald? Republicans Don’t watch what they say to rile up the base, watch what they do with their money when push comes to shove. When the chips are down and RFK causes a treatable disease to rip through the population people will be lined up for treatment.. That or in 3 years (or possibly next year) the Dems will neuter him and we’ll be back to letting big pharma run things

STONKLEAPS

very suspicious. a director at $CRSP bought 990K shares on the open market for 51.5M - sounds liek conviction to me

STONKLEAPS

Buy out rumors on CRSP, prone to moon.

Zealousideal-Dig8410

CRSP Therapeutics & Big Bear A.I

EightFolding

The decision depends on whether you want to focus on growth (SCHG) or want to hold a fund that tracks the performance of the CRSP US Total Market Index (VTI). Two entirely different tools, different aims. If you want to track the index but add a growth tilt you could split it between them.

LongLiveAnalogue

Fuck man what about his CRSP DD. What’s his ERA so far?

STONKLEAPS

CRSP going to bounce hard

STONKLEAPS

CRSP will be the GOAT of biotech

EscapeHistorical178

TTWO DIS BA JNJ CRSP PLTR CALLS ON SPY, pull the trigger. MAKE MONEY, LFG.

CompatibleDowngrade

Also long CYBN in addition to CRSP and BEAM. Probably going to index though going forward because it’s hard to pick winners!

STONKLEAPS

anyone feel like CRSP is the biggest sleeper stock right now.

StophJS

What's on your watchlist for the dip? I am tempted to buy up a bunch of CRSP right now but would be selling VT to do it and therefore taking on a lot of additional risk.

Kitchen_Catch3183

If S&P 500 is garbage then the CRSP U.S. Total Market Index is turbo garbage.

Inner-Atmosphere8954

Anyone else holding CRSP calls?

chatrep

This is for my aggressive growth portfolio that I hope to keep for 5-10 years and also good stocks to wheel. RDDT ASTS NBIS CRSP HOOD TSM SMR My 401k is S&P index fund SPLG My main brokerage will move to VGT I mention this to highlight not everything is in these aggressive growth stocks.

TheRootOfMostEvil

CRSP gonna 2x by next year. I’m heavily bought in

krazay88

Holy shit i just noticed how NTLA got absolutely crushed the other day! Absolutely insane dump, I’ve learned my lesson already with bio stocks, but wow thank god I didn’t get greedy and buy into it after I had successfully rode the CRSP pump.