Reddit Posts
Vertex Pharma (VRTX)-the next Blockbuster for 2024
Ok, the loss of TTWO was expected, but why CRSP. I slept in and it's all gone.
CRSP FDA Approval Deadline Dec 8.
SPECIAL DATES IN MEDICAL HISTORY **NEXT MONTH**= FDA DECISIONS= Dec 8th 2023 FOR $CRSP & Dec 20th 2023 FOR $BLUE-Aprvd in UK Last Week.
CRSP Stock Surges after winning the first ever gene editing approval
CRSP 10k YOLO "First-Ever Gene-Editing Drug"
$CRSP play - possible first ever FDA Approval of Gene Editing treatment - Dec 8th PDUFA
beat Cathie Wood at her own agme (kinda) crispr time is ripe folks
beat Cathie Wood at her own agme (kinda) crispr time is ripe folks
beat Cathie Wood at her own agme (kinda) crispr time is ripe folks
VERVE therepeutics potential for the next boom boom?
CRSPR, Intellia, Beam, Pacific Biosciences, Illumnia, Editas, Invitae... Will any of these companies be huge in the future?
CRSP gets FDA panel support for sickle cell treatment.
What top 3 Bags are holding right now? And how much do you hate yourself?
Where can you find summaries of the historical fundamentals for an index?
Tale of the epic comeback…. Started with oil, ended with oil….
Moved from trading to investing. Question about losing positions.
Start Investing in ETFs: Growth ETF and Total World ETF
$CRSP CRISPR Therapeutics pending EMA and FDA Aprovel
~$18k gains, holding for a few months since the low. ignore the -100% its an error, hopefully ; )
Could Fidelity be hiding the fees of its zero ER funds?
5 Top-Ranked Small-Cap ETFs to Buy for the January Effect
5 Top-Ranked Small-Cap ETFs to Buy for the January Effect
MULN, NIO Stock Speculations. TSLA Stock Blitzed. BIIB CRSP & VRTX Stock...
$CRSP More or less 15% short that is a lot
Diversified Portfolio with Individual US stocks - 2023
What are your thoughts on ARKG ETF now as a long-term play?
$CRSP formed a cup and handle! It’s taking off 🚀. Let’s go BULLS!!! ☕️ 🐂
The biotech rocket getting ready for launch - $CRSP Crispr Therapeutics DD
What are YOUR long term holds? And is a large percentage of it tech- why or why not?
CRISPR DD that's not only lazy, but also manages to stack a few levels of uncertainly, meaning only a fool would give this any credence...
Only 4% of US stocks from 1926-2016 outperformed one-month T-Bills!!!
My portfolio is trash. Should I sell all of it?
Big Pharma destroying small cap Biotech SGMO
Where’s the volume for gene editing stocks (CRSP, EDIT, NTLA, BEAM, etc.)?
Am I crazy for buying the following stocks at the prices listed here?
Research: The History and Evolution of SPACs, The Causes of the SPAC Boom, Why Companies SPAC, and Who Invests in SPACs
Opportunities in Options Around Earnings This Week
Opportunities in Options Around Earnings This Week
Opportunities in Options Around Earnings This Week
My bearish vertical put spread expired in-the-money. I think I lost the total value of the spread
DD on DTIL (gene editing company) I am hoping people can critique
Your next hard-on? What’s your next intrinsically undervalued target for DD then buy/option?
All this talk about $CSCR and no discussion about $CRSP
Romancing the Wood - a TA/DD of your favorite, can't possibly fail, Cathie Wood investments! (TSLA, CRSP, PLTR, WKHS, TDOC, ROKU, SQ, JD, BABA & HOOD)
My main positions are getting too expensive to dollar cost average
Actionable Trading MRNA SRPT CRSP GSK PFE MODERNA HITS $100 Billion GENE RNA MED
$NTLA and $REGN announce that they have successfully corrected a hereditary disease with an infusion of CRISPR
$NTLA and $REGN announce that they have successfully corrected a hereditary disease with an infusion of CRISPR
NTLA, CRSP, EDIT, BEAM, VERV, ARKG likely to fly on Monday
NTLA, BEAM, CRSP, VERV, EDIT, and ARKG likely to fly on Monday
Mentions
CRSP, game changing healthcare technology to potentially cure genetic diseases
Most people don’t have patience for 5 years, but if you do: CRSP
Agree on CRSP. Great potential and they’re having exciting trial results. I would love to hear your take on LUMN. I almost bought it earlier this month but didn’t. They’re up 18% since then and now I’m kicking myself.
Should I yolo my 90 year old mothers savings into $CRSP $BEAM and $NTLA ?
Sorry that and CRSP. Lmao. Your post history is crazy bro
Good lord bought some CRSP calls just for it to drop 5% in the last 10 fuckin minutes
Man that pos stock I sold as soon as I broke even, fkn CRSP randomly dumps 5-10 percent in a day
oh look more $CRSP insider buying
As I mentioned in another comment, the benchmark uses the MSCI indices for each country, gross return (i.e. inclusive of dividends), denominated in USD. Specifically, it uses the investable market index (IMI), which also includes smaller companies. There isn't an ETF product directly linked to the MSCI USA IMI index, but this is basically completely correlated with the CRSP US Total Stock Market index, to which VTI is benchmarked. They basically [move together](https://i.imgur.com/JCuCF1c.png). There also aren't ideal country-specific ETF products to track the IMI. For instance, the [MSCI China IMI index](https://www.msci.com/indexes/index/664216) has 784 holdings, but Blackrock's MCHI tracks MSCI China, not the IMI, and only has 550 holdings. It also has an expense ratio of 0.59%, and similary across the board for all the country-specific ETFs. You do get a better comparison if you go with broad international ETFs, instead of country specific ones: - Blackrock's IDEV tracks the MSCI World ex USA IMI index for 0.04% (developed ex-US). - Blackrock's IEMG tracks the MSCI Emerging Markets IMI index for 0.07%. As you can see, there is some slight tracking error between the ETFs and the indices they track, but it has actually favored the ETFs so far this year (i.e. better for investors).
I expect RSP to underperform SPY but it'll still be green. Just not as good as the monster money printers. And tbf, most of history is a few winners. Old comment of mine: Turns out stock-picking is not so easy that anybody can do it and most stocks are crap. >“The results also help to explain why active strategies, which tend to be poorly diversified, most often underperform,” says Bessembinder, who found that the largest returns come from very few stocks overall — **just 86 stocks have accounted for $16 trillion in wealth creation, half of the stock market total, over the past 90 years.** https://wpcarey.asu.edu/department-finance/faculty-research/do-stocks-outperform-treasury-bills Competition, new disruptive threats means companies go bust and lose often: >I calculate that the approximately 25,300 companies that issued stocks appearing in the CRSP common stock database since 1926 are collectively responsible for lifetime shareholder wealth creation of nearly $35 trillion, measured as of December 2016. However, just five firms (Exxon Mobile, Apple, Microsoft, General Electric, and International Business Machines) account for 10% of the total wealth creation. The 90 top-performing companies, **slightly more than one-third of 1% of the companies that have listed common stock, collectively account for over half of the wealth creation.** The 1,092 top- performing companies, slightly more than 4% of the total, account for all of the net wealth creation. That is, the remaining 96% of companies whose common stock has appeared in the CRSP data collectively generate lifetime dollar gains that matched gains on one-month Treasury bills. https://papers.ssrn.com/sol3/papers.cfm?abstract_id=2900447
Revenge investing is a good way to lose more money. Not saying it's a bad idea to invest in stocks, but you'd be starting investments in SHOP, PLTR after huge earnings gaps, NVDA after it has doubled in 3 months with no pause, and CRSP which is probably just as risky as the biotech that destroyed your account. You lost thousands by not having a plan. So have one before you just randomly throw $200/week at stocks.
Turns out stock-picking is not so easy that any retard can do it and most stocks are shit. >“The results also help to explain why active strategies, which tend to be poorly diversified, most often underperform,” says Bessembinder, who found that the largest returns come from very few stocks overall — **just 86 stocks have accounted for $16 trillion in wealth creation, half of the stock market total, over the past 90 years.** https://wpcarey.asu.edu/department-finance/faculty-research/do-stocks-outperform-treasury-bills Competition, new disruptive threats means companies go bust and lose often. And that's great for society. >I calculate that the approximately 25,300 companies that issued stocks appearing in the CRSP common stock database since 1926 are collectively responsible for lifetime shareholder wealth creation of nearly $35 trillion, measured as of December 2016. However, just five firms (Exxon Mobile, Apple, Microsoft, General Electric, and International Business Machines) account for 10% of the total wealth creation. The 90 top-performing companies, **slightly more than one-third of 1% of the companies that have listed common stock, collectively account for over half of the wealth creation.** The 1,092 top- performing companies, slightly more than 4% of the total, account for all of the net wealth creation. That is, the remaining 96% of companies whose common stock has appeared in the CRSP data collectively generate lifetime dollar gains that matched gains on one-month Treasury bills. https://papers.ssrn.com/sol3/papers.cfm?abstract_id=2900447
CRSP crash is a leading indicator, risk off is beginning
for real though why did that director drop $50M on CRSP
Look for calls on CRSP and AEVA instead.
Selling my OCT expiry CRSP puts somewhere between \~$51.50 and \~$47.
CRSP fuckin me today with a surprise earnings release. There goes my port ☹️
Since fucking when was CRSP reporting today??
It's another r/collapse for retards like you. Go back in your hole. >Equal weight has been getting crushed and some people trade things other than SPY sir. It’s like 3 companies holding this together There's a reason why SPX is not equal weighted? Lmao. You act like this isn't 100% normal. Turns out stock-picking is not so easy that any retard can do it and most stocks are shit. >“The results also help to explain why active strategies, which tend to be poorly diversified, most often underperform,” says Bessembinder, who found that the largest returns come from very few stocks overall — **just 86 stocks have accounted for $16 trillion in wealth creation, half of the stock market total, over the past 90 years.** https://wpcarey.asu.edu/department-finance/faculty-research/do-stocks-outperform-treasury-bills Competition, new disruptive threats means companies go bust and lose often. And that's great for society. >I calculate that the approximately 25,300 companies that issued stocks appearing in the CRSP common stock database since 1926 are collectively responsible for lifetime shareholder wealth creation of nearly $35 trillion, measured as of December 2016. However, just five firms (Exxon Mobile, Apple, Microsoft, General Electric, and International Business Machines) account for 10% of the total wealth creation. The 90 top-performing companies, **slightly more than one-third of 1% of the companies that have listed common stock, collectively account for over half of the wealth creation.** The 1,092 top- performing companies, slightly more than 4% of the total, account for all of the net wealth creation. That is, the remaining 96% of companies whose common stock has appeared in the CRSP data collectively generate lifetime dollar gains that matched gains on one-month Treasury bills. https://papers.ssrn.com/sol3/papers.cfm?abstract_id=2900447
CRSP - Casgevy sales updates at 4:30 via VRTX
CRSP is gapping up right now Large volume orders after crossing $59 Think this could run back to $70+ this week
CRSP running on the daily into expected earnings/updates…
$CRSP could fly tonight with $VRTX providing CASGEVY results
You almost always miss the boat following the herd. For those of us married to the game we are dialed in to as much pertinent information as possible. If I don’t know the answer, I know someone that does know. If you miss it there is someone else to dance with. The answer to your question is yes there are more like Nvidia. You probably won’t see them on Reddit though. One of the beginning stages of investing is what should I buy? Eventually as you become more nuanced you find plenty of stocks you can buy. The question ceases to exist. Then it becomes about the money to be able to invest in those ideas. Some stocks I think have big potential for growth in that space. RXRX-CRSP-ARM are a couple in my AI portfolio. The strategy has no trailing stops and we are buying on the dips until 2030. CRSP is one of the rare situations where fundamentals aren’t a major consideration. We are investing in the potential of the technology. I still think this has the potential to be a ten-bagger and possibly mint some millionaires.
Yup. Just added ITM leaps for CRSP, HOOD, ASTS, TOS. We’ll see how the next 6-12 months shapes up.
Get ready for CRSP to skyrocket this morning 🎉
Are you buying any dips today? We could go down more but who knows? Picking up some CRSP ahead of next week earnings
Why are CRISPR stocks ($BEAM, $CRSP, $NTLA) so heavily shorted?
Aug22 CRSP call. Just closing my eyes and pointing
CRSP calls An insider literally bought $50 million worth of stock two weeks ago Earnings early next week, including VRTX update on Casgevy sales Generous dip yesterday was due to NVO and UNH dragging down the whole sector
So I’ve used ChatGPT in a loosely similar manner, and the complexity of the prompt (plus deep level follow on conversation) is what really helps drill down to what you’re looking for. Based on a lengthy discussion about thesis, aggressiveness, convictions, etc, I asked it to recommend 10 stocks to round out exposure in key areas, and it recommended BLK, COIN, VRTX, REGN, NTLA, CRSP, SNOW, PDYN, SMR, and ARKW ETF. I made purchases of three of these and I’m up ~40% since.
Went balls deep in CRSP calls for next week’s earnings
still thinking about the CRSP insider who bought $51M worth of shares lol
I like CRSP calls here
Cathie Woods offloads CRSP... now it will rise lol
I’m in $IBB and $CRSP
Internationally based stocks. Im in on CRSP, N u holdings, and Rolls Royce. Trying to hedge against US BS lol.
CRSP $50mil insider purchase, readouts coming, ER in 2 weeks
Long: RKLB NVDA TSLA CRSP Mid: Saving for above. Short: Think about saving for above.
CRSP $50mil insider purchase, readouts coming, ER in 2 weeks
That’s a great point RE: non-dilutive capital raise. I didn’t know they were exploring that. CRSP did the same thing- they gave Vertex 10% more of the casgevy profit share for $1B in cash
CRSP is definitely better positioned regarding cash. Though last earning call Intellia’s CFO was pretty confident about capital position and pointed out that in 2-3 year timeframe also collaboration or some royalty arrangement could be subsitute/addition to the capital raise. Either way, I am quite confident on the future of both companies.
Director of CRSP just dropped $50mil which has a $5B market cap. One of the largest insider purchases of any company. That’s twice the money for a company 2% the size of UNH. And CRSP is curing disease. UNH is denying disease. Fuck UNH.
CRSP is a pretty easy swing trade, likes to pop up and down a lot, but rarely keeps dumping
Looking like CRSP and the whole gene-editing space could be the next big thing.
I am holding it for the long term, although given the recent massive insider buy from SR One, the short term seems very enticing too. Wait out biotech until phase 3 success or approval and there will be no upside. By the time phase 3 starts, they are usually sufficiently de-risked. Phase 2 is where the most gains are usually made. As for semaglutide beating it to market and eating its lunch in CVD: No study has shown semaglutide reduces CVD risk in non-diabetics or people with normal BMI (not obese). And based on how it works, it wouldn’t reduce CVD risk in those populations anywhere near mainstay treatments. It would be complimentary to a subset of the patient population at best. The reason why it reduces CVD risk in diabetics and obese individuals is mainly because it treats diabetes and obesity, meaning diabetes and obesity themselves are risk factors for CVD. The genes CRSP’s CVD pipeline targets are among the most genetically validated targets in CVD. Lp(a) is high in 20% of the population, and is worse than LDL-C and there is not treatment for it on the market. Its gene is known, and it has been almost eliminated in studies and CRSP’s own trial. Same with ANGPTL3 for LDL and TG and AGT for hypertension. These are all proven endpoints for clinical trials in CVD. Noncompliance is a huge issues in medicine in general, especially CVD patient population. Semaglutide and the like are extremely overblown by the media and celebrity doctors. They’re not a magical drug. They’re just more obese people than lay people realized. What is CRSP is targeting is proven. The effect they will have on the risk of CVD is proven. That’s why they are validates clinical endpoints. Proven, in biology, means a lot. Not many others can claim that. Why? Because these genes are known based on loss of function mutations in humans to have these effects. So, in a sense, the clinical trial has already been done. What’s actually being tested is the toxicity and gene delivery modality. And the initial toxicity data that just came out looks great. And the gene editing platform, using crispr instead of prime editing or newer modalities like its competitors is a better strategy because it has a much longer track record, we know more about it, and the off target effects based on studies is so minimal that even if you used other modalities it wouldn’t make a difference and would come with much more significant trade offs.
They have active trials, an approved therapy, and IMO best gene therapy platform. I have a medical background so I have some knowledge in this space. If there in vivo pipeline works, there will be a CURE for hypertension and high cholesterol. Basically eliminating all CVD risk. Noncompliance for CVD is very high. This is one and done. Also those a million other biotechs are usually 1 or 2 trials away from insolvency. CRSP has probably the best balance sheet of any.
Dude I was waiting for CRSP to cure COVID. They're doing a lot of cool shit I'm too dumb to understand right now, call me back when they have something marketable, until then there's a million other biopharmas to gamble on with active trials
CRSP is going to pop off when it can cure herpes
JIM CRAMER just said CRSP “CAN TRIPLE FROM HERE OR STAY FLAT. GREAT SPECULATIVE STOCK”. With all the momentum behind it recently, take that as you will.
Extremely large insider purchase of $50mil by director of CRSP. Not just any, guy. The managing partner of SR One, GSK’s corporate vc arm spinout. He knows what pharma looks for. Best balance sheet of any biotech, 30% short interest, blockbuster potential pipeline. LOAD UP.
CRSP perfect squeeze candidate backed by solid balance sheet and pipeline. Get in before too late.
Staying with CRSP and the biotech stocks, been quite the good ride!
CRSP - Director bought 1% of the company a few days ago. There is many reasons why a director might sell, but only one reason for him to buy! Earnings next week!!
CRSP - Director just bought 1% of the company with earnings next week... Usually directors will sell for various reasons, but they only buy for 1 reason!
Look at CRSP. Huge squeeze potential and a lot of great news.
I stopped paying attention to CRSP when they lost the patent case on the technology. It was always the biggest issue for me. If you don't own the tech, then there's no future for you as a company. The technology is world changing. But who owns it?
I've been bagholding since '21. I drank the CRSPR koolaid back then and also bought EDIT and CRBU. I even got the Jennifer Doudna "Crack in Creation" audiobook and listened to that. Any thoughts on Caribou (CRBU)? CRSP and EDIT and a few others are the traditional plays. I've felt ok holding those and think they'll make ATH again someday. Not sure about CRBU though. That's a stock I feel I got suckered into.
My capital is small right now so I use smaller PT just in case I get assigned. I use SMCI, CRSP, AVXL, ALAB, ACHR, OKLO, QBTS, CRWV, sometimes CRCL.
I’ve been deep researching next plays… taking a serious look at CRSP. My hesitation is I’ve always felt it was amazing advancement and would break out past couple of years but it just sort of stalls. I am particularly bullish on CTX310. Unlike the niche editing, this has massive implications. I too suspect an acquisition before this fully materializes post trials.
Tempted to buy some CRSP
Hell yeah I put half of my Roth IRA into CRSP a few weeks ago. 500 shares strong. I don’t really mess with options but happy for you man, great DD a few weeks ago and I appreciate the research and content 🙏🏼 General market sentiment is getting frothy like 2021, but CRSP has a truly revolutionary pipeline. If you sold your options and bought shares for the long haul, you will have millions
Today bought 15 of CRSP Aug15'25 70 CALL, already 20% down in after hours - considering selling tomorrow at open. Hold or sell?? im panicking lol.
Today bought 15 of CRSP Aug15'25 70 CALL, already 20% down in after hours - considering selling tomorrow at open. Hold or sell?? im panicking lol.
Today bought 15 of CRSP Aug15'25 70 CALL, already 20% down in after hours - considering selling tomorrow at open. Hold or sell?? im panicking lol.
CRISPR Therapeutics, CRSP
CRSP is big and will only get bigger. The biggest road block to this is the possibility of regulations, but we all know the speed of the government.
CRSP been moving steady i like it
Might has well bring back CRSP now that we're OPENing old tickers. I'm in.
Great summary DD for CRSP. I think the acquisition potentially is pretty high given its enterprise value is around $4B and its tax shield. If casgevy picks up significantly Vertex may want to acquire them to secure the remain 40% profit share + additional diabetes cell replacement candidates. I could see someone buying them for $10B EV, or $140/sh
CRSP continues to pick up steam. I was in it for the long-term AI fueled upside, but the history of the director who purchase $51 million in shares last week suggests that it might also be an acquisition target.
#TLDR --- Ticker: CRSP Direction: Up Prognosis: Buy shares, the director just dropped $50M on it. Catalyst: Massive insider buy, upcoming readouts for in-vivo therapies, Casgevy revenue ramp-up. Positions: 463 shares @ $54 avg.
CRSP. Solid balance sheet, strong game changing pipeline with positive phase 1 just released and more readouts in coming months. Director who’s also managing partner of SR One, the biotech VC firm that spun out of GSK, just bought $50mil of stock - largest insider purchase in many years. Stock up %18 after buy. 70% institutional ownership. 30% short interest. Perfect short squeeze candidate. Load up.
This morning is vintage WSB meme vibes. When I see CRSP and OPEN pumping its like we got the boys back together.
Friends, dont miss CRSP, next stop 100$ 🚀🚀🚀
"I've heard that I should wait to buy after 8/1 due to the US tariff situation." People don't wait for certain dates to react to something. They take it into account when they hear about it, consider how likely it is, etc. There has been so much focus on tariffs while the market is up 26% off the April low. There will absolutely be a correction at some point and I wouldn't be surprised if that correction is due to something other than tariffs. "Other stocks im currently interested in are CRSP ONDS JOBY AMPX" I think one has to realize that we're back in a sort of 2020/21 environment where evvvverrrrryyyyone wants to own the RKLB, ASTS, PLTR, etc stocks that go up every day. That works until it doesn't and there is a point where it stops being about valuation or anything correlated to where the company is, it's just pure FOMO chasing. You had a period in 2020/21 where people acted as if a lot of stories were going to happen tomorrow when the stories were going to happen maybe in 5+ years if not much longer. CMPS is a great example - shroom stocks, which was a big topic on here at the time. CMPS IPO'd, went up about 100% in a short time then proceeded to lose about 92% in the years since. BYND was a nearly $250 stock at one point now it's $3.50. Not saying that RKLB or ASTS are bad stocks (I am long both but from much lower levels), but all of this sort of early/earlier stage stuff there is something to the idea that the stocks can get ahead/far ahead of where the companies are and when the music stops it looks like 2022 or early 2025. RKLB is up 105% YTD, but when the market tanked earlier this year it lost nearly 50%. The music will stop at times and if you have a portfolio full of speculative/very speculative stocks, don't be surprised when it's down 30-40-50% in a hurry. "I don't want to miss out on potential gains and get major FOMO" ASTS is up 150% since the end of May. It's already FOMO at this point. Given age it's good to have risk, but you want to allocate risk in a way that is sustainable - if another early 2025 happened tomorrow and you had a portfolio full of stuff like this "CRSP ONDS JOBY AMPX" would you dump it all? How do you allocate in a way that gets you through good times in the market and shitty times because there's going to be lousy days/weeks/months and years (2022 wassn't that long ago.)
check out my WSB DD on CRSP
AMPX still room to go. CRSP too
CRSP.... I sider bought 51 Million position. I did some DD on this guy and he never losses. He sells for way more all the time. Insiders don't throw that money unless they expect 200% gains
I've been posting about CRSP lately - check out my DD/updates if you're interested
What made you take CRSP calls ?
Congrats on CRSP profits! It has big retail community, and this company is the future of medicine.
Nice!!! I bought 25k worth of CRSP yesterday after CEO bought a huge amount of shares. I'll take it
I've been in TMC for months. Also OMEX and WWR. CRSP long.
CRSP from 60 to 50 and back to 65 in just about a week
thinking about buying HOME and CRSP 10K each next week and holding on to them for at least 1 year, thought?