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Caribou Biosciences, Inc. (NASDAQ:CRBU) was the recipient of some unusual options trading activity on Monday. Investors bought 2,867 call options on the company. This is an increase of 726% compared to the average volume of 347 call options. 🚀
I called CRBU, now I’m calling CABA next. Minimum 100% gainz from here.
$CRBU successful cancer treatment???
What is buzzing now: 5 tickers traders keep pinging
CRBU 200%, IPSC same since and trades below cash likely next one.
CRBU just blew up around 170% +
GTIM sold today for 100% gains on the $2.5 calls. Next is CRBU calls. Expecting minimum 100%
CRBU gains still holding. Volume spiking with price and readouts are coming out anytime between now and Dec 31st
CRBU & INMB Investors: How Are You Positioning Ahead of Clinical Data & Upcoming Trials?
Top 8 Breakout Candidates for the week of 8/30
Mentions
I'm in $CMPX, been getting knocked around pretty hard. 43% short where institutions own 75+% of shares. 52 mil available. Oct 24th is the next catalyst (decision on application) anybody been looking at this? Also $SPRO $OTLK, and $CRBU. Lol went on a bit of a shopping spree with $SLS profits.
I sold CRBU end of December for the tax offset. Feel dumb about the reason I bought it in the first place. Some rando on Reddit in a CRSP post mentioned CRBU and that was enough for me. No DD really, just some random guy on Reddit who sounded smart and thought it was a good buy. I've had a few of those.
CRBU. They’re a biotech company making allogenic car-T cell therapies for multiple myeloma and non Hodgkin’s lymphoma. Crispr Gene editing but instead of a 3-5 week wait to receive treatment it’s off the shelf and outpatient which increases TAM by 9x compared to the billion dollar therapies that exist rn. Their lead drug has RMAT, orphan drug, and FDA fast track designations and the second drug in the pipeline just got RMAT designation this week. They have 150M in cash which gives them runway to 2H 2027 and their market cap is around 200M rn. When the next set of data drops stock will go from 2.00 to either 13.00 or .30 not much in between
Surprised no one mentioned CRISPR stocks like CRSP NTLA CRBU
I have been in Caribou for quite some time. I have had to dollar cost average down to reduce my break even price point. Pro’s- I am a big fan of Rachel and of their progress in CB10 and CB11. I am glad they focused on oncology and shelved the autoimmune research (for now). Their benchmark is Yescarta, an autologous treatment that already generates $2.5B per year, so there is a proven scalable larger market for CRBU’s allogenic approach. Cons - the share price action is terrible. Rachel did waste one full year by not starting HLA matching sooner but that is in the past and the results speak for themselves. My biggest issue is that I don’t understand the price movement. Seems like it’s held down for accumulation. There are significant amounts of large institutional holders. I understand the science and the results so I am staying in and buying when it gets to these low points. I haven’t sold a share in 4yrs so yes, some shares (not many) are near ATHs.
Along with CRBU, have you looked at EDIT and NTLA? One person that ties these all together is Jennifer Doudna. Looking into her was how I found out about CRBU years ago. I agree with their financial responsibility, and they've maintained it over the years. I think this with the relationship to Doudna are important as the companies are serious and aren't at risk of "being stupid" (e.g. out of nowhere turning into a crypto treasury company like Leap Therapeutics). If you are able to share those RE tickers, I would like to know or at least know a good source for them to save me a search. Would appreciate it greatly.
The thing about CRBU is that I still have them on my watchlist. Purely because they had very good financials - which is rare for a biotech company and signals responsibility when it comes to financing. I don't know if OPEN will be affected by this build up. But generally it has to do with the Trumps push for cheaper housing (like the 50 year mortgage etc.). When you look at the details it makes housing "more affordable" but at the same time generates a lot more income. The real estate market suffered because of a housing crisis (expensive houses, bad mortgages) and because this is actively being tackled there's a big chance it will boom (and maybe even OPEN will boom because of it). The only thing that can somewhat confirm this further is big funds reallocating money to RE tickers.
A little over 2 weeks ago wasn't very long ago, haha. But yes, I suppose it depends on where you bought. It looks like for CRBU in particular you had bought in a small window where the price was relatively high. It's odd that it went down so much from its insane pre-market leap. Sounds like you did well betting against AMD at its ATH and in this current climate. If you don't min me asking, where is a good place to read about the heat building up in the real estate market? Are you referring to the likes of $OPEN and REITs?
NBIS and CRWV did the same to me along w ACHR CRBU and TWST
CRWV NBIS CRBU ACHR are all assaulting me. pray for my port
Early Warning Watchlist, based on a spike in relative volume / today's short volume activity: RAY (477% short) CURR (137% short) ACRV (251% short) NFE (3.2% short) *Early Early Early warning . . .* GFAI (4.1% short) SNDL (5.5% short) *WTF? stocks:* THAR (798% short) CRBU (137% short)
lol I posted about it a while back when I bought it. Here is the link to the CRBU post: https://www.reddit.com/r/smallstreetbets/s/pKCiQiTrPk
Ok just to be clear, we don’t know how long you had CRBU before “calling” it, but when you made that post it had just peaked and was on its way down. Maybe if you had called it over the summer…
Interesting insight and I think I will factor it more into my strategy with CRBU! The premiums for this ticker are currently not the best (partially because of the overall status of the market). You have however gave me the confidence to write more CCs at a lower strike price. This makes me speculate that their play will be to try and get it approve around 2026 Q2/Q3 in order to be able to raise money. Hence I will probably exit around that time if it happens (and possibly rebuy after the price drop)
Well just because you have positive news in a phase 1 clinical does not mean “you’ll get fast-tracked through fda approvals.” There are other worse conditions with fewer treatment options that get held up by the fda all the time. Car-T therapy is very complex and has a host of potential side effects. This stock spiked today because of its phase 1 data, it likely fell back down to earth because of the length of time it will require for any potential approval. The phase 1 data looked promising but they still have to design, enroll, and perform a phase 2 study. Not to mention the all important phase 3. This may take years and risks considerable devaluation of the stock. You also have to keep in mind, there are other companies currently performing similar clinical trials. If they were to have a bad readout that would be very bad for this stock. Or if they were to have a very positive readout before CRBU finished phase 2 that may be bad for the stock.
CRBU announces they used their new chRDNA platform to create two gene therapies with 0 off target edits 0 graft v host and 90% response rate. Stock launches 200% premarket and bleeds out all the gains???
Wish some stocks here had more short stock availability. Mspr just then was the most obvious short at $0.8 sideways trading after a huge pump. Phio was another likely short at $4.4 sideways trading at resistance in premarket. Arec too, same story as Mspr, with sideways trading around $5.5 after a huge pump. Msai was less obvious, although none of the stocks I just mentioned had shorts available anyway so whatever. For the ones that did actually have SSA, glad to have shorted CRBU for a nice profit near its premarket high today, and scalped a small short win on Dvlt and Femy on open.
Buy CRBU the next INTS
Given the surge premarket, I think entry into CRBU at this price isn't too bad. Also watching IOVA for an entry because their data seemed pretty promising.
https://www.stocktitan.net/news/CRBU/caribou-biosciences-announces-positive-data-from-ca-m-mouflage-phase-la0ji00s4wh2.html Summary of the recent announcement
I'm in and to be fair. This was absolute luck. I created a bio basket bet just past week and CRBU was one of ten stocks
What is CRBU doing. Pre-market is up 180%. I wonder if they really found something or if they plan to rug pull me by noon just for fun.
That's not entirely true, since often enough stocks like that incl. the DD behind why there is an upside are shared on Reddit. Two examples I personally caught are GME back in the day and BYND just last week. In both cases, the posts on Reddit were enough to get me to do my own research and then enter with a small position based on my usual risk management. In case of CRBU you can also find a couple of posts across several different sub-reddits within the last couple of weeks.
If you are late to CRBU, pls consider ACRV!
Thanks brotha. Next is CRBU $2 calls for 1/16/26. Expecting 100%+ again here
Yesszir. It usually never hits that amount of time and I’ll always sell before then. Next is CRBU $2 calls 1/16/26 expiry
I'm liking what CRBU is doing for me today.
Crispr-cas9 is the hot thing in biotech right now. It’s used for gene editing and in the future gene editing will be able to solve basically any disease ever. CRBU is co-founded by the woman who co-invented the tech and also co-founded NTLA. She is working with CRBU to develope a crispr hybrid RNA-DNA (chRDNA). This chRDNA will make the existing crispr tech work better be more accurate and have less unintended gene edits which have unintended consequences. ChRDNA will make crispr safer and more effective, it is also a platform that can be patented and then CRBU can license it to all the other biotech crispr companies and make billions. Trial data for their two proof of concept therapies CB-010 and CB-011 will be released by end of year. Stock has moved from 0.66 to 2.60 in anticipation but mcap is still around 300m which means this has upside potential to easily 10-20x if the results are good. I’m betting on the competence of Jennifer Dounda who invented crispr, won a Nobel prize, and cofounded NTLA. Bad results kills the thesis but she has proven to be a good bet and the upside far outward the downside here.
If CRBU trials come out good what’s a realistic market cap? Crspr is 6.5 billion and CRBUs chRDNA is basically just an improvement to crispr cas9 tech.
“what’s the next biotech to triple like NTLA” maybe the other company founded by the NTLA founder? CRBU leaps cause crispr is the future
Now I’m telling you CRBU $2 calls for 1/16/26 expiry
PFE most likely will buyout CRBU as well stepping into CRISPR space
CRBU and NTLA. What are your thoughts? Of course I'm a bag holder
EDIT, CRBU, CBUS. I do really like ABAT, though I sold because so many battery players in the game right now. HIT is a great long-term stock methinks. I think TLRY has a chance a recapturing significant value after earnings and if/once Trump DEA announces rescheduling of THC to Schedule III.
Long-term: CRBU, CBUS, EDIT, PACB. As usual. Short-term: IXHL (as everyone knows), and also TLRY. Earnings next week for TLRY and if Trump Admin announces rescheduling of marijuana to Schedule III, look out.
You think that's fun. Look at CRBU. And imagine you bought near the bottom
Same as always: CRBU, EDIT, CBUS. long term gene editing stocks. I think WSB is pumping DNUT now. They move quickly lol
Thank you, love the animal stocks. Seem to surge (Gorilla GRRR, Caribou CRBU, Wolf WOLF,) There's 2 dragonfly's (Dragonfly Draganfly)
I've been bagholding since '21. I drank the CRSPR koolaid back then and also bought EDIT and CRBU. I even got the Jennifer Doudna "Crack in Creation" audiobook and listened to that. Any thoughts on Caribou (CRBU)? CRSP and EDIT and a few others are the traditional plays. I've felt ok holding those and think they'll make ATH again someday. Not sure about CRBU though. That's a stock I feel I got suckered into.
Okay, I bit man. 641 shares @0.78. I’m hoping at least one of my Alzheimer’s/Dementia/biotech plays will workout very long term. Currently in $ALZN, $CLLS, $CRBU, $PACB, $SGMO, $TNXP, $UNCY, $VXRT. Now adding $CGTX to that list. All went in for around $500. Some are up, some are down. Likely holding until moon or zero.
You all can keep chasing your white whales. I'll just keep DCA'ing on EDIT, CRBU, and CBUS every time one of them dumps in the morning hours.
I will continue to shill for long-term plays: CRISPR/gene editing stocks EDIT, CRBU, and CBUS. Also will continue to support anyone that wants to jump into ASBP as an end-of-August play. Looking to get back into IXHL if it starts to slide back to a realist price, as we haven't seen data yet. Really just want to go take gains once again before the stock craps out for a while while it can't actually produce the drugs it's studying OPEN looks like it may have but those who didn't get out, but it could pump. I think the next big stock with a possible squeeze is UGRO
Now is the time to get into gene editing. Plenty of companies under 5$ (EDIT, CRBU, CBUS, PACB) that have moonshot potential the MOMENT one of their gene therapies works out. CBUS is already rolling out altered agriculture products and getting paid royalties - a big hitter once people realize how fucked we are when it comes to soil/water/heat conditions next twenty years.
This is one of the few penny stocks (along with CRISPR stocks CRBU, CBUS, EDIT) that I like long-term. Technology that will be EXTREMELY potent in the future.
All of them follow the same trend - EDIT, CRBU, NTLA, PACB The "smaller" CRISPR stocks hit higher percentage gains but take bigger beatings, too. The ones I'd be interested in optioning would be EDIT and CRBU. But I'd rather buy the shares outright TBH
CRBU, IXHL, OPEN I only have a position in CRBU fwiw
If you are looking for a serious answer, my money would be on one of the CRISPr gene-editing companies. EDIT, CRBU, BEAM, NTLX, CRSP. Some have already begun utilizing their sequencing to save lives. Others are beginning to patent additional sequencing. I think the BIG one will come when a company realizes how to edit agricultural genetic code to utilize less nutrients, and grow in harsher climates.
I believe CRBU has a great potential with its allogeneic CAR-T therapies for hematological cancers and autoimmune diseases and its current valuation which is lower than peers.
CRBU has gone from $1.85/share in the past couple of months to nearly $3 now. A good option to take a look at.
CRISPR Therapeutics and Vertex Pharma. I have about three percent of my total portfolio in gene editing stocks (CRSP/VRTX/NTLA/CRBU). Very risky investments IMO, but I'm planning to hold them all for decades. In the case of CRSP/VRTX, my time horizon is forever.
is this stock better than CRBU? maybe i should cut down research time on CRBU and focus on this IMTX
Guys lets push $CRBU to the moon, do it for me
Guys can we get $CRBU up, I’m broke
$CRBU is going to go up pretty fast
I have a boat load of CRSP/CRBU shares in my IRA but other than that no
Crispr stocks: NTLA, EDIT, CRSP, BEAM, CRBU (maybe wait for a bit more drop on this one), also RIVN
https://preview.redd.it/3nfk4ntdthpc1.jpeg?width=1284&format=pjpg&auto=webp&s=3844304a00c093b6dbb962846e428c4cb86acfbd $CRBU insiders are loading up great chance to buy cheap
$CRBU, do it now before its too late. Long term option call hold in expire in October just watch
No I’m holding all major players but at different position sizes based on my confidence in the company, CRSP is my largest position by far but that’s also because it’s grown a lot recently, followed by NTLA, BEAM, VERV, CRBU, PRME, EDIT, GRPH
CRBU, they have a crucial clinical trial result coming out in March.
10$ Long call on $CRBU expiring in Oct. the stock is up 36% since Jan. Option up 17% today. 👌👌👌🔥
10$ Long call on $CRBU expiring in Oct. the stock is up 36% since Jan. Option up 17% today. Trust this one boys👍
Biotech are like lottery tickets, find one with something that hasn’t been approved yet and buy it low, and wait. You either win the morning they get fda approval for whatever drug, or they dilute/RS you into oblivion. I’m holding DARE, ARDX, and XLO, and watching CRBU, CARM, and PLX.
Acknowledged! Thanks for the write-up. I have a large bagholder position in CRSP too. I drank the Crispr tech kool aid and am also bagholding EDIT and CRBU. I'm not in MRNA anymore but it's always on my watchlist. I bought it in the mid 20s at the start of the pandemic and sold when it doubled, which was very painful as I watched it 10x after I sold. If it falls back near to my sell price I might get back in.
If these biotech companies come out with good clinical results or interest comes back to biotechs, these biotechs are an easy 2 to 3x. I am personally bullish on CRBU, Dr Jeniffer Doudna (inventor of Crispr) is cofounder and they have made many complete remissions from cancer in Phase1 trial which is why Pfizer ended up buying 25m$ equity in it.
Buy more CRBU. Always.
Here is CRBU’s latest presentation. https://investor.cariboubio.com/static-files/3168b9f6-48dd-4e44-8103-df5ff9013b6b
ALLO is a good bet and so is Caribou Biosciences (CRBU). They had many remissions in Phase 1 Trials and looks promising for Car-T cell therapy.
You could find a discounted stock like CRBU who just has Pfizer make a significant investment in their cancer/lymphoma genetic based research. I picked up a few units today for my portfolio.
I'm invested in CRBU, that's why I asked.
What do you think about their investment into Caribou Biosciences (CRBU)?
The only good thing about PFE is that they just invested in gene editor CRBU.
$CRBU bag holders Lmao 
$CRBU Crash will be awesome to see
$CRBU will crash and leave Bag holders with losses
$CRBU Crash incoming Lmao
💰💰💰Get new runners in our app! #premarket #watchlist 07/6 $MULN - Announces $25 Million Stock Buyback Program (+66%), $AKU - no news + big volume (+30%) $CRBU - Announces $25 Million Equity Investment from Pfizer (+21%), $KZIA - awarded Fast Track Designation (FTD) by the United States Food and Drug Administration (FDA) (+18%) https://preview.redd.it/x8hbkiuubcab1.jpeg?width=576&format=pjpg&auto=webp&v=enabled&s=5e8cb6dcec140e8d7a6c2981d695b7cc16a5ab06
💰💰💰Get new runners! #premarket #watchlist 07/6 $MULN - Announces $25 Million Stock Buyback Program (+66%), $AKU - no news + big volume (+30%) $CRBU - Announces $25 Million Equity Investment from Pfizer (+21%), $KZIA - awarded Fast Track Designation (FTD) by the United States Food and Drug Administration (FDA) (+18%) https://preview.redd.it/dbkb6qksbcab1.jpeg?width=576&format=pjpg&auto=webp&v=enabled&s=0b4c0de621a1c4ac5f30168f782051ff28652279
30k as an emergency fund. The rest I would take a chance and split between two genomics stocks. Probably CRBU and CRSP. If that works out I would sell at some point and dump it all into VOO or SPY on pullbacks and sell calls
I have 1/3rd of my portfolio allocated for micro and small caps that have the potential to 10x or more. These are the high risk, not yet profitable companies with huge upside potential. So far most of mine are green energy and biotech related \-SAVA (Alzheimer's stage 3 drug) \-CRBU ( crisper genome cell therapies ) \-EOSE (zinc battery grid storage, lithium alternative) \-EXROF (EV efficient car parts) \-EEMMF (lithium) Enphase was previously on this list when I started buying at $15 and it became my first 1,000% gain. Looking for more ideas... What are your top 2 picks and why?