Reddit Posts
I went through Airbnb's last two 10-Ks. A third of their profit isn't from hosting. It's from the Fed, and that's unwinding
BCHT - same playbook as SKLZ & AIXI: $78.4M judgment in collection, $40M MC, lock-up active, zero dilution risk & conference catalysts May 4–7
$BCHT - same playbook as SKLZ & AIXI: $78.4M judgment in collection, ~$40M MC, lock-up live, zero dilution risk & conference catalysts May 4–7
$BCHT - same playbook as SKLZ & AIXI: $78.4M judgment in collection, $40M MC, lock-up intact, zero dilution risk & conference catalysts May 4–7
$BCHT - SKLZ & AIXI playbook redux: $78.4M judgment in collection, $40M MC, lock-up live, no dilution risk, conference catalysts May 4–7
QHSLab (OTCQB:USAQ) Reports 127% Year-Over-Year ISP Growth and Launches Q-Connect GLP-1 Support Assessment
New DJT Tweet will benefit domestic pharma and generic suppliers $ELTP
$NRXP News Update :NRx Pharmaceuticals Advances Robotic-Enabled Transcranial Magnetic Stimulation Combined with Neuroplastic Therapy for Military and First Responder Applications
AZTR Azitra- Everyone’s focused on the red… but you’re missing the setup
AZTR AZITRA - Everyone’s focused on the red… but you’re missing the setup
AZTR Azitra - Waiting for the storm to blow off.
AZTR AZITRA - Everyone’s focused on the red… but you’re missing the setup
AZTR - This is a ticking time bomb. Financing closed, CEO is all-in, and June data is going to send this.
I started tracking when politicians trade stocks before votes. Found a few interesting ones
I started tracking when politicians trade stocks before votes. Found a few interesting ones
Holy crap, VCX up nearly 200%, AZTR x2, SMCI options printing – Reddit alert chain reaction in full effect?
Vireo Growth Inc. Announces Fourth Quarter 2025 Results
Republican lawmakers shrug at more funding for Iran war - Politico
A D.C. energy expert's analysis when the Strait will re-open
$CVVY - The Sulfur Company Hiding in Plain Sight as a Gas Producer (And the Market Has No Idea) [DD]
$CVVY — The Sulfur Company Hiding in Plain Sight as a Gas Producer (And the Market Has No Idea) [DD]
Cloudastructure Deploys Solar-Powered AI Security Enclosures Across Multiple States, Expanding Critical Infrastructure Protection
Himmy ($HIMS) is steps away from disrupting Big Pharma
BioVaxys (CSE: BIOV | OTCQB: BVAXF) Reports Positive Phase 2 Data for Maveropepimut (MVP-S) + Pembrolizumab and Low-Dose Cyclophosphamide in Metastatic Bladder Cancer
Possibility of Profiting due to Current Events?
Intel shares plunge 17% on weak Q1 guidance - worst day since 2020
$BVAXF $BIOV.CN BioVaxys Reports Positive Clinical Study Results from Phase 1B/2 PESCO Trial of MVP-S with Pembrolizumab
Genprex (GNPX), small biotech startup from Austin, TX to develop cancer and diabetes treatment?
BioVaxys Technology Corp. (CSE: BIOV | OTCQB: BVAXF) Announces Phase 1 Clinical Study Results Advancing DPX(TM)-Formulated Products in Patients with Non-Muscle Invasive Bladder Cancer
NASDAQ : ONCY : Oncolytics Biotech® Expands Its Gastrointestinal Tumor Scientific Advisory Board with the Addition of Dr. Eileen O’Reilly, Dr. Neil Segal, and Dr. Van Morris
BioVaxys (CSE: BIOV | OTCQB: BVAXF) Announces Positive Phase 1 Clinical Study
$LKY.ax | $LKYRF We have released a new company update video with our MD and CEO Kerrie Matthews.
[DD] The "Critical Minerals" Arms Race is Here. Why I’m Betting on Trigg Minerals ($TMGLF) as the Next Defense Supply Chain Play
$LKY.ax | $LKYRF MD and CEO Kerrie Matthews on site with high grade stibnite from our Mojave Project, demonstrating the quality of the antimony mineralisation we are progressing.
AMD jumped today and I only caught it because of AI
A Look At Cardiol Therapeutics Inc. (CRDL)
Locksley Resources Limited (ASX: $LKY; OTCQX: $LKYRF) due diligence
SPECTRAL AI ($MDAI) $150M Gov.BACKED!! Next Big Play!!
RenovoRx Expands Scientific Advisory Board with Internationally Renowned Interventional Oncologist, Thierry de Baère, MD, PhD
RenovoRx Expands Scientific Advisory Board with Internationally Renowned Interventional Oncologist, Thierry de Baère, MD, PhD
TNMG Updated DD — New PICTOLINE Japan deal and +40% since the last thread
TNMG — H1 FY25 snapshot + Dec 9 “AI Agents” forum (OpenAI Podcast host speaking).
TNMG — H1 FY25 snapshot + Dec 9 “AI Agents” forum (OpenAI Podcast host speaking).
The Next RR? $TNMG — Dec 9 ‘AI Agents’ + OpenAI on stage, $3.50 PT (Potential 8×) 🚀🚀🚀
NAKA Stock / The Kindly MD Bitcoin Treasury - Look at the Monthly Chart
$CAPR Follow-Up After about a 7% gain today and looking to have solid SS potential coming up in Q4
$CAPR might squeeze soon as MD drug regains FDA support after resubmission for approval
I am shorting UNH - Very High Quality DD
$PSTV - Why Just 10 Percent of CNSide’s Market by End of 2026 = $24 to $48 per Share (Conservative Case) and Why Reyobiq Could Multiply That
$504 Billion AI Healthcare Revolution Accelerates as Corporate Giants Launch Next-Gen Platforms
$504 Billion AI Healthcare Revolution Accelerates as Corporate Giants Launch Next-Gen Platforms
$504 Billion AI Healthcare Revolution Accelerates as Corporate Giants Launch Next-Gen Platforms
$504 Billion AI Healthcare Revolution Accelerates as Corporate Giants Launch Next-Gen Platforms
817% gain over 13 months. Thoughts on my trading thesis?
PSTV is locked, loaded, and ready to blow.
PSTV is locked, loaded, and ready to blow.
Allogene Therapeutics (ALLO): Why This Beaten-Down Biotech Could 🚀
SNYR (Synergy) - 8 quarters profitable, new Coca-Cola executive with new products and international expansion
CAPR: Regulatory Chess, Institutional Tension, and One Hell of a Setup
CTM Castellum finally breaking out & a Deep-dive into their 3 Subsidiaries
Toyota Industries' shares nosedive on $33 billion buyout deal
$WFLD/Leonovus RTO Update – Fresh Insights from Leonovus MD&A (May 30, 2025)
$WFLD/Leonovus RTO Update – Frische Einblicke aus Leonovus MD&A (30. Mai 2025)
AYR Announces Delay of Q1 2025 Financial Statements and MD&A, Expected Cease Trade Order and Strategic Review Process
ERNA (Eterna Therapeutics) - My DD on a potential 3-5x bagger under $1
14,460 Shares in Roadzen, Inc. (NASDAQ:RDZN) Acquired by Price T Rowe Associates Inc. MD
14,460 Shares in Roadzen, Inc. (NASDAQ:RDZN) Acquired by Price T Rowe Associates Inc. MD
14,460 Shares in Roadzen, Inc. (NASDAQ:RDZN) Acquired by Price T Rowe Associates Inc. MD
14,460 Shares in Roadzen, Inc. (NASDAQ:RDZN) Acquired by Price T Rowe Associates Inc. MD
YOLOD in KDLY on the pump on Monday at 15, now 7, 50% down in 48h, am I Regarded?
YOLOD in KDLY on the pump on Monday at 15, now 7, 50% down in 48h, am I Regarded?
Sony Calls Off $10 Billion Merger With Indian TV Giant Zee Entertainment Enterprises
MedBright AI (MBAI.c MBAIF): 9 Clinics, 3 Provinces, 21 Dermatologists, 5 Mohs Surgeons, 2 Plastic Surgeons, and 13 General Practitioners
Integrated Cyber Solutions Inc. Provides Status Report of Annual Financial Statements and MD&A (CSE: ICS)
Luca Mining Corp. $LUCMF (otc) or $LUCA (tsxv) Filed their financial statement but it wasn't picked up by the news services
American Aires Inc. Announces Positive EBITDA with Its Filing of Q3/2023 Financial Statements, and MD&A
American Aires Inc. Announces Positive EBITDA with Its Filing of Q3/2023 Financial Statements, and MD&A
Breaking news: Novel triple combination developed by CanBas shows promise as third-line treatment in patients with metastatic PDAC
Breaking news: Novel triple combination developed by CanBas shows promise as third-line treatment in patients with metastatic PDAC
Breaking news: Novel triple combination developed by CanBas shows promise as third-line treatment in patients with metastatic PDAC
Mentions
After researching all day it seems my main options are try to say the magic words to my doctor and then maybe wait 6 months for a slot Or see if $NOWL goes up 300% by fall and then I goto the fanciest Harvard MD ass private practice and get seen same day It seems the main risk difference is proximity to emergency care. But there’s a clinic across the street from a hospital in my city $NOWL baby we got this 🤞🤞🚀🚀🚀🚀
Great breakdown on fundamental analysis! One thing I'd add for newer investors - learn to read the actual SEC filings, not just the summaries. The MD&A section often buries important risk disclosures that analysts gloss over. Also worth learning to spot red flags: auditor changes, related-party transactions, and going-concern language in footnotes. These are signals that often precede major problems. Tools like scamdunk.com are useful for spotting patterns like this. The best fundamental analysts I've seen combine quantitative screening with deep qualitative reading of primary sources.
You: hey a good thing was announced at this company. Me, Dr.Stock Genius, MD: priced in
I run out of tokens by noon typically these days - used to be like 2PM but with every new version the token to output ratio gets tighter. Not sure what plan we're on at work but it isn't giving us much to work with these days, and I feel it's cutting out earlier and earlier every day. That isn't my big issue though - my big issue is that even with an MD file 'properly' guiding Claude processes, I'm only successfully generating quality content about 80% of the time. When it's on its on, and it's a huge help, but there days where Claude just randomly ignores the MD file and literally admits to guessing on items that (per the MD) need confirmation on ambiguity. So what about those days where I spend my tokens to have Claude just guess and shit out randomly generated garbage, then admits in chat to guessing? I just paid for that. Do I get my money back? Yesterday was a dogsiit day for me with Claude. We'd love to automate our processes with AI but it's just getting more and more expensive (soon will be more expensive vs. overseas team members) and it just randomly has 'bad days' where if we took what it shit out as gospel, we'd be tits up pretty quick.
No, it doesn’t. You’re looking at the Selected Financial Data in the S-1, which is not typically audited. This is essentially MD&A. Their audited financial statements are included by reference and audited by PWC, as is commonly done.
You pay for a PhD, trust me. The 4-6 years you spent making liters of pee in a grad lab could’ve been spent at a higher compensated corporate job laying the foundations for your future career. This of course varies depending on the type of PhD you received, but the unfortunate truth is that you don’t need a PhD to do science unlike an MD or JF which is needed to practice law or medicine.
Yeah, I started with the 10$, but OPUS quickly ate through the session limit, so I said fuck it, might as well go for the 100$ tier, and I'm glad I did. Best AI in the game by far. I was stunned when it just spit out an entire .MD file on its own without my asking. Absolutely incredible.
Do you live in MD? I do.
To be fair he said “so go out and buy a dell, they’re great” directly after talking about how Michael Dell started out by making great computers and the “just never stopped” (quoting MD)… it’s a bit of a stretch the claim people making that he specifically told people to buy $DELL the stock. It was all in the context of talking about people who had donated to the t-word accounts. With that said I have stake in Dell stocks and if people misinterpreting his statement as “buy $DELL” and that causes the value to go up, I’m not complaining
My husband is in Big Law. These people have no idea how little a million is to these places. Hell, sometimes they pay it to a speaker at a lunch. My cousin came back to them after a stint in the military (he ran off to be a Marine helicopter pilot for 10 years after 9/11 and got an age waiver) and they handed him several million dollars to play with. When he left them he was a MD..but for writing foreign options trading programs. He had never traded an account before. He had no idea what he was doing but they had to take him back (it was the law..I don’t understand it) and his previous job no longer existed so this was their solution. He lost a couple of million before we assume he got laid off. He was stressing all the time about it. He took a year long trip across the country after they did one of their massive worker lay offs. He is now doing his old job again at a smaller investment bank down South. So yes, they blow stupid money all the time...like giving millions to a high level computer programmer and seeing what he will do with it.🤣
As someone working in STEM research and medicine, all modern research in whatever disease you study to be taken seriously involves some level of sequencing. And Illumina has been the best for a while. I will focus on cancer. So if you are doing cancer research you are going to be sequencing patient tumor samples and so on. Based on research we have treatments for these diseases too where there are certain drugs and clinical trials that depend on a patient having X mutation in Y gene for instance. Some premier institutes like DFCI, UCSF, MD Anderson make sure to sequence every one of their patients often times at no cost to the patient as they want to treat them as best as possible. So to put it plainly, sequencing is crucial and what a decent chunk of modern medicine will be based on (i.e. precision medicine where you give drugs to specific patients based on the genetic profile of their disease, whether it's cancer, ALS, or whatnot). And so hospitals and research institutes use Illumina sequencers and it's mainstay. Now the question is, this stuff is still pretty expensive in terms of machines and reagents to run (although thousands of thousands of times cheaper than it was even 10 years ago, similar to moore's law basically with transistors Sequencing has gotten a shit ton cheaper). Idk the exact economics of if / when it will start printing money. But it's basically something that is super technologically advanced and crucial to the field of medicine at this point. Maybe there's some sort of consumer play like with how computers started as something only big institutes had but then everyone now has a laptop, iphone etc. idk
Yes, it does. Did you listen to CEO on the conference call? This was an easy read. What do you think the expenditure is going sometimes not everything is inside information or dumb luck. This was purely about listening to smart leaders, giving proper guidance and releasing innovative new products. MD has a huge line of chips and cards coming out this half of 2026 that’s what everybody has been waiting for and investing on for the past year and a half. You missed the boat cry.
We just went to 4.79 here in MD. Up from 4.39 last week.
MD Code Red - poured, Zin can - locked and loaded, dopamine? Already IV crushed. My body is ready
Chick fil a is fckingnasty in MD
Megadoodoo Megadoodoo MD
I have confidence in these systems. IEL I told claude to rewrite an entire 3rd party library (\~50k LOC) - by extracting the functions I use in isolation, into a local copy, then ensure correctness, then optimize it (check every function, try to improve / optimize by FIRST doing a high level logic scan, then a test, where you write a function that outputs OLD output, then NEW output (new function) and A-B tests over 1million+ iterations. Anything sensitive gets 100 million random iterations. Put this into my MD file / the flow (happens for every test). \--- The test compound onto each other - and i redundantly check / verify logic like 2-3-4 times (just like i would in a team). I send the tests to DIFFERENT agents who lack context of each other to independently verify. Shit works EXTREMELY well... today was my first > 10k LOC changed day.
Holding long term. This one is is a multibagger. The 100% long-term survival + complete tumor clearance with PD-1 combo in syngeneic ovarian models is eye-catchine. The BEST part is the strong MD Anderson tie-in. The work is led by Dr. Michael Andreeff (Professor at MD Anderson), who has been involved in the development and preclinical studies of ERNA-101. They’re planning a clinical proof-of-concept trial in platinum-resistant ovarian cancer in collaboration with MD Anderson. That’s a legit research partner, very hard to get accepted . Just bought some
Solid catalyst on a micro-float name. The 100% long-term survival + complete tumor clearance with PD-1 combo in syngeneic ovarian models is eye-catching, especially for a cold tumor like ovarian cancer where immunotherapy often struggles. What stands out even more is the strong MD Anderson tie-in. The work is led by Dr. Michael Andreeff (Professor at MD Anderson), who has been involved in the development and preclinical studies of ERNA-101. They’re planning a clinical proof-of-concept trial in platinum-resistant ovarian cancer in collaboration with MD Anderson. That’s a legit research partner, not some random academic group. Just bought some
Lower than VP which is lower than Director and Executive Director. ED Isnt even that high up, the real management layer starts at MD
**F**acebook **A**mazon **A**pple **A**MD **G**oogle Netflix has been dethroned.
I pulled the cannabis investments from Chicago Atlantic SEC filings to see what companies may be next on Vireo Growth's radar. These are investments classified as "cannabis" as of late 2025 and whatever notes I have on them. Cresco, Verano, Archos Capital (Verano), Terrascend, and Fluent (now Vireo) are the MSOs. * **TheraTrue** \- Georgia medical. New CEO as of June 2025 came from Deep Roots Harvest right after Vireo acquired them. The CEO he replaced was Victor Mancebo, who is a board member of Vireo Growth. * **Kaleafa** \- Oregon. Was the partner for Eaze to enter Oregon years ago. Vireo recently bought Eaze assets. * **BeLeaf Medical** \- Missouri. Their co-founder was part of the three person team that launched Bud Light for AB InBev in the 80's. Also associated with Nature's Care dispensary in Illinois, which is/was with Acreage. * **Oasis (AZ GOAT AZ)** \- AYR assets that were first bought by AYR then sold back to the original owners. * **HA-MD LLC** \- Maryland. Ethos brand. Vireo partnered with them in 2023. * **Dreamfields Brands** \- This is the Jeeter cannabis brand. Big pre-roll brand. Just moved into New York in late 2025. * **Aeriz Holdings** \- Chicago based. Has ops in AZ and CA too I think. They do aeroponic growing. * **Kapple Holdings (Cannabis & Glass)** \- Washington. Owner is also co-founder of Iowa Cannabis Company. * **Shangri-La** \- Missouri based. Operations in Illinois, Ohio, and Connecticut. * **Silver Therapeutics** \- Massachusetts. Operations in Maine, Vermont, and New York. * **Subsero Holdings** \- Illinois. * **Elevation Cannabis** \- Oregon, California, New Mexico. * **Wellgreens 2.0** \- California. Chicago Atlantic's cannabis investments are a partnership with Silver Spike Capital. The executive chairman of this partnership was the founder of Silver Spike and was a **board member of WeedMaps until he stepped down when they announced delisting**. Silver Spike is the company that took WeedMaps public, with WeedMaps now actively looking to move into cannabis. I have been thinking WeedMaps was making a move into Florida because of their lobbying, but Fluent/Vireo might have already been part of the Florida move? Chicago Atlantic also added **Robert Beasley** as a partner after they acquired Fluent, where Beasley was CEO. He was a OG executive at Liberty Health, where Vireo board member Victor Mancebo (see above) was CEO. Robert Beasley recently took over as CEO of a **Michigan cannabis company Common Citizen**. He only operated in Florida cannabis in the past. If you look at his LinkedIn it goes: * Fluent (Jan '20 - Aug '25) * Chicago Atlantic (Aug '25 - Dec '25) - head of restructuring * Common Citizen (Dec '25 - Jan '26) - joins as CEO amid their restructuring * Chicago Atlantic (Feb '26 - present) - partner Common Citizen was also an investment by the Aphria insiders (SOL Global) in 2021. These guys were investors or strongly connected to other Vireo connected companies such as Fluent, Liberty Health, Verano, Cresco, and The Flowery. The SOL guys go way back to Liberty Health in 2017 with Robert Beasley.
The issue with Reddit and people in general is they think their situation is normal and representative of others. I am one of the people considered very rich here, I am an MD in drug development in my early 40s. I am lucky enough to have studied outside the US and therefore have never had any loans. I live in a VHCOL area where the average house price in my town of 100k people is $1.75 million. Every single person in my team at work of maybe 50 people are millionaires at least on paper, same with everyone in my neighborhood. I am under no illusion that my situation is representative of anyone else apart from me, and those in my immediate circle.
instead of a loan, I'd rather go with a balance transfer with low interest. There are a lot currently [https://milesopedia.com/en/best-credit-cards-in-canada/transfer/?utm\_source=MD&utm\_medium=referral&utm\_campaign=communaute](https://milesopedia.com/en/best-credit-cards-in-canada/transfer/?utm_source=MD&utm_medium=referral&utm_campaign=communaute)
It's the cost of doing business to be at the top of the food chain. People want to be near DC, and so does business. It's incredible just how much NVA has grown the past 20 years. My grandparents lived in Fredrick. The growth has been insane. Even that far out in MD.
Nah. Analyst->Associate->VP->ED->MD.
Director title only exists because mid level bankers were tired of sitting around as VPs for a decade before getting the MD nod.
She is not that high. ED could be considered senior middle management / entry upper management. If she was an MD, that’s the real club.
KITL Reverse Merger news The Company also highlighted the appointment of its new CEO, Dr. Ajit Dhaliwal, MD, MBA, whose leadership is expected to drive innovation, brand elevation, and national expansion initiatives. Dr. Dhaliwal earned his MD from The Royal College of Surgeons in Ireland. He completed an Internal Medicine Residency at The Mount Sinai Icahn School of Medicine in New York City. In addition, he obtained his MBA from Quantic School of Business and Technology. Dr. Dhaliwal comments: "I am incredibly excited to step into the role of CEO and lead this transformative chapter for KITL. When Jim and I first discussed this combination, what struck me immediately was the alignment - a publicly traded platform ready for a bold new direction, and a proven clinical model built to scale. Regenerative medicine and aesthetic wellness are not just trends; they are the future of how Americans will approach their health. People are demanding more. More precision, more accountability, more results - and that is exactly what Regen Health Physicians delivers. https://preview.redd.it/jbpnwvw9z8yg1.jpeg?width=1179&format=pjpg&auto=webp&s=3ec689096bd17678a08c8e2be9889b10e1375f69
It isn't just the biotech sector. For the past 10, almost 20 years, most corporation have trend towards downsizing or completely eliminated their R&D department in a bid to focus on the operational and business verticals. Most corporation aren't willing to underwrite R&D risk anymore. This has led to the rise and flourishing of startups that, if successful, are acquired, to be integrated into the core business of the buying company. I had a good part of my feet on the venture capital side and quant side of my professional career. **Iova is worth looking into.** They have two lines of product: Amtagvi (FDA approved for advanced melenoma with best in - class ORR, with consistency shown years after FDA approved) and Proleukin. >**52% Amtagvi Response Rate with Two or Fewer Prior Lines of Therapy 73% Overall Disease Control Rate** >SAN CARLOS, Calif., Feb. 05, 2026 (GLOBE NEWSWIRE) -- Iovance Biotherapeutics, Inc. (NASDAQ: IOVA), a commercial biotechnology company focused on innovating, developing, and delivering novel polyclonal tumor infiltrating lymphocyte (TIL) therapies for patients with cancer, today announced data demonstrating a best-in-class profile for commercial Amtagvi^(®) (lifileucel) with unprecedented response rates in a real-world clinical, retrospective study in patients with advanced (unresectable or metastatic) melanoma. Amtagvi is the first one-time T cell therapy for a solid tumor cancer as well as the only FDA-approved treatment for advanced melanoma patients previously treated with anti-PD-1 and targeted therapy, where applicable. >The real-world results were highlighted in an [oral presentation](https://www.iovance.com/scientific-publications-presentations/) at the 2026 Tandem Meetings of the American Society for Transplantation and Cellular Therapy (ASTCT^(®)) and the Center for International Blood and Marrow Transplant Research (CIBMTR^(®)) in Salt Lake City, UT. >Forty-one evaluable patients with previously treated advanced melanoma received commercial Amtagvi according to the U.S. prescribing information at four authorized treatment centers. The physician-assessed confirmed objective response rate (ORR) was 44% (18/41) and the disease control rate was 73% (30/41). Response rates were higher with earlier Amtagvi treatment. The ORR was 52% (12/23) following two or fewer lines of therapy compared to an ORR of 33% (6/18) after three or more lines of therapy. The unprecedented real-world response rates also improved upon the 31% ORR in the C-144-01 clinical trial that supported the U.S. FDA accelerated approval of Amtagvi. >Lilit Karapetyan, MD, MS of H. Lee Moffitt Cancer Center & Research Institute stated, “The real-world response rate builds on existing clinical data and supports consideration of lifileucel as soon as possible after immune checkpoint inhibitor treatment. An overall response rate of 44% was observed in the full cohort, with a 52% response rate among patients treated in earlier lines of therapy. I am encouraged by the potential for an increasing number of patients to benefit as adoption of TIL therapy continues.” >Daniel Kirby, Chief Commercial Officer of Iovance, stated, “The real world Amtagvi data with impressive response rates, paired with unprecedented five-year durability and survival data, demonstrate a best-in-class profile and better outcomes in patients treated earlier.” >Previously treated advanced melanoma represents an unmet medical need with more than 8,000 annual U.S. deaths.^(1) More than half of patients treated with first line standard of care will progress within 12 months.^(2) The U.S. FDA granted accelerated approval for Amtagvi in February 2024 based on ORR and duration of response (DOR) from the C-144-01 clinical trial. The published [final five-year analysis](https://ascopubs.org/doi/10.1200/JCO-25-00765) demonstrated unprecedented durability and follow-up in previously treated advanced melanoma patients, with \~31% ORR, median DOR of 36+ months, and a 20% five-year overall survival.^(3) Iovance is conducting TILVANCE-301, a Phase 3 clinical trial in frontline advanced melanoma, to confirm clinical benefit. >1. National Cancer Institute Surveillance, Epidemiology and End Results (SEER) Program. 2025 Estimates. [https://seer.cancer.gov](https://seer.cancer.gov/) (accessed February 2026) 2. Larkin J, et al. NEJM; Robert C, et al. Lancet; Tawbi HA, et al. NEJM 3. Medina T, et al. JCO Source: [https://ir.iovance.com/news-releases/news-release-details/best-class-real-world-data-support-early-amtagvir-treatment](https://ir.iovance.com/news-releases/news-release-details/best-class-real-world-data-support-early-amtagvir-treatment) **Using what made Amtagvi/ lifileucel successful, Iova has made positive in-road into cell therapy for soft tissue sarcomas with a high 50% ORR.** >Iovance Announces Positive Results from the First Clinical Trial for TIL Cell Therapy in Soft Tissue Sarcomas *50% Objective Response Rate (ORR) in Advanced Sarcomas* >*Significant Market Opportunity with More than 8,000 Patients Diagnosed* *Annually in the U.S. and Europe* >SAN CARLOS, Calif., Feb. 24, 2026 (GLOBE NEWSWIRE) -- Iovance Biotherapeutics, Inc. (NASDAQ: IOVA), a commercial biotechnology company focused on innovating, developing, and delivering novel polyclonal tumor infiltrating lymphocyte (TIL) therapies for patients with cancer, today announced positive early data from a [pilot clinical trial](https://clinicaltrials.gov/study/NCT05607095?cond=sarcoma&intr=TIL&rank=6) led by Memorial Sloan Kettering Cancer Center (MSKCC) and supported by Iovance of lifileucel in patients with advanced (metastatic or unresectable) undifferentiated pleomorphic sarcoma (UPS) or dedifferentiated liposarcoma (DDLPS) who were refractory to at least one prior line of systemic therapy. >Among the first six evaluable patients treated with lifileucel monotherapy, physician-assessed confirmed ORR by RECIST v1.1 was 50%. All evaluable patients had advanced disease, were refractory to prior therapy, and had significant disease burden, with a mean sum of diameters of 117 millimeters at baseline and a mean of more than two prior lines of therapy. Patients experienced deep responses that improved over time, consistent with lifileucel in melanoma, non-small-cell lung cancer, and other solid tumors. The safety profile was favorable and consistent with lifileucel therapy in other indications. Based on these results, Iovance plans to commence a single arm registrational trial in second-line advanced UPS and DDLPS in the second quarter of 2026 and will engage with the U.S. Food and Drug Administration (FDA) on an accelerated path to expedite approval. Iovance also plans to explore lifileucel in other high grade soft tissue sarcoma subtypes with high unmet need as part of its clinical development program. >UPS and DDLPS are high grade, aggressive soft tissue sarcomas associated with poor prognosis that impact more than 3,000 patients in the U.S. and more than 5,000 patients in Europe annually, including more than 3,500 patients with advanced disease.^(1-3) There is a high unmet medical need for new treatment options for second-line patients with recent clinical studies reporting ORRs of less than 5%, median progression-free survival (mPFS) of \~2-3 months, and median overall survival (mOS) of \~9-10 months.^(4-6) >Lauren Baker Banks, MD, PhD, Sarcoma Medical Oncologist, MSKCC, stated, “In the first clinical trial of a TIL cell therapy in UPS and DDLPS, one-time treatment with lifileucel demonstrated compelling and unprecedented response rates with the potential to address a significant unmet need in patients who are refractory to frontline standard of care. Patients with UPS and DDLPS suffer from high disease burden, poor quality of life, and a lack of effective treatments, including no approved immunotherapy options. In the second-line setting, mPFS for many patients is only a few months with mOS less than a year. We look forward to presenting these results at a medical conference in 2026.” >Dr. Brian Gastman, EVP Translational Medicine and Research at Iovance, stated, “The exciting clinical results show that lifileucel could offer a new, highly efficacious, and durable immunotherapy option in two aggressive forms of advanced sarcoma and further illustrate the promise of our TIL cell therapy platform to offer meaningful clinical benefit in multiple solid tumor cancers. Chemotherapy with extremely poor efficacy remains the second-line standard of care for these patients after progression on front-line chemotherapy. We look forward to bringing lifileucel to UPS and DDPLS patients as quickly as possible.” Source: [https://ir.iovance.com/news-releases/news-release-details/iovance-announces-positive-results-first-clinical-trial-til-cell](https://ir.iovance.com/news-releases/news-release-details/iovance-announces-positive-results-first-clinical-trial-til-cell) More: [https://ir.iovance.com/news-events/press-releases](https://ir.iovance.com/news-events/press-releases)
Good god I’m up so much on ghey-MD
Plot twist, it was MD Burry.
Thermo puts was easiest play this year. They laid off my local DC/MD sales account rep of 10+ years and now my account rep is 10 states away in Houston
Nothing like the greasy stripper pole route to MD.
It's a scam. Almost all healthcare business startups are either MD-owned or VC owned. In neither of those cases would they be reaching out to just some guy for $50k. Also, $50k for a 10% ownership of just about any medical clinic is an absurd payoff. Many clinics make $1m per year. Too good to be true.
"Though war pestilence and famine ravage the land, stonks only go up! PRAISE ALLAH" \-Dr. Jesus H. Trump MD.
Thanks, I appreciate it alot. I will get started soon. I already spent a few days on learning the terminology, the purpose of option trading etc but as you said, there is alot to learn and it gets overwhelming when things don't click and you keep reading/finding same things over and over again. I use AI to summarize so that I can memorize/re-visit easily, and sometimes to explain it in different ways that I can understand. After some time, the agents learn about your style, especially if you are using local agents + MD files for skills and memory. Hoping to share some good hits here in the future, thanks to you all :)
Dang good thing I just opened a Fidelity account back up & can trade OTC! You make a good argument; I always liked their products, living in MD 🤙
RXDX - Prometheus Biosciences. A friend is a researcher who worked for them. Probably the most brilliant man I’ve ever met. Genius level MD. The stock was at $27 when I realised he worked for them and I said to myself I should buy but I procrastinated and bought in around about a year later at $170. Beyer swooped in and bought them for $200 per share. Not a bad return but 7.4x would have been a lot nicer.
I think there’s intelligence classes like there are economic ones and if you’re in the middle class of intelligence you can realistically do 90% of white collar work so unless it requires a license like being a fuckin MD or something, lie if you have to to get the job. Fuck em.
Let the bears have some hope. Jesus MD is going to get a big bear hug from Winnie the Pooh, if that‘s not ATH news nothing is. Praise be to Allah!
i think you're confusing a dream of yours with an episode of *Dr. Christ MD*
Problem with LLMS is they are stupid don;t use GPT it sucks, use claude or an open source model, Open claw has a bynch of security flaws btw. So be super careful, prompt injection risk is real. I don't think they will lead to AGI, it is likely some other tech that will. Pro tip, use MD files to save xontext on Claude and you can do proxy reinfrocemnt learning and have the chat update context so it remembers. Saves a ton on compute credits
A law degree is closer to an MD (not including residency) than a PhD.
Doing the MD in an A sorta way.
Dude, read your employment documents. You've got a degree, so I'm guessing you're at least literate. As long as you're not working for some bro in his basement I bet this company even has a code of ethics and compliance. Finally, why don't you take all the money you likely don't have, put it in your pocket, and go and ask the PM or your MD what the policy is. Depending on what your firm trades you likely have a restricted list, but as long as you're not managing private SMAs for accounts you might be good if you start away from those. Don't complain to us ya dummy, go look it up and ask ffs. Nobody there is going to blame you for asking. Hell, just talk to one of your coworkers first if you're not totally autistic.
Two HC-130J Combat King II aircraft and MD-500 Defender (MH-6 Little Bird) helicopter
A6 Hibino Free Diary and a A5 Midori MD, both grid lined. Highly recommend both.
FWIW the new regs on controlled substances, including Adderall, are nonsensical. My MD is limited in the amount she can subscribe, so she's dropping dosages for her patients. Had a dosage that finally worked, and then this insanity. Thanks, Obama!
Actual double board certified MD. No snake oil salesman here.
But none of what he says sounds like true severe and rapidly progressing dementia. I hate the whole "his health is in rapid declined" argument. The fact is that for his age, his stamina is remarkable. He plays golf, flies to meetings and gives energetic speeches when needed. The same can be said for what Biden did at his age. Ask yourself...how many almost 80 year olds do you see out just doing shit, let alone golfing and traveling the world attending meetings and briefings. Even if he's hopped on coke, Adderall, or falling asleep half the time. I'm an MD who deals primarily with the elderly and if I had a patient he and Biden's age just "doing shit", I'd be very pleased with their activity level. He just genuinely sounds like a babbling idiot. He doesn't have to be demented AND a painfully narcissistic moron to be doing what he's doing. I say this as someone who has zero respect for him and nothing but I'll will towards he and his entire vile family. I happily voted against him 3 times.
There is no single switch you can flip in SEC filings to bulk export “retention metrics” because the SEC does not mandate a standard DAU or NRR metric, and companies disclose them in different sections, formats, and even with changing definitions over time. In practice, you either have to combine a bit of manual work with a “brain friendly” workflow, or lean on tools that already structure this kind of KPI data. A practical approach is to identify a small KPI set you care about, then consistently pull those from each company’s 10 K and 10 Q MD&A or KPI sections into your own sheet or database, accepting that Snap’s DAU or HubSpot’s NRR will not be defined exactly like Netflix or Spotify. If you want something more automated, your best bet is to use a financial data API or LLM based extractor pointed at the filings or earnings decks, then spot check the outputs against the original documents so you are not blindly trusting the model
I invest in bios, and I understand some people don’t like them, but here are two I feel strongly about: $SLS - It’s only available at these prices because of past toxic financing deals which are behind them now. Some of the best cancer hospitals in the world are part of their development in Memorial Sloan Kettering, Moffitt Cancer Center, and MD Anderson. Their current phase 3 REGAL trial is derisked as they come. Here is the best DD I’ve ever seen on it: https://www.reddit.com/r/ValueInvesting/s/s3pjFlirzN $CING - new time released, once daily ADHD med about to hit the market. Experienced management and ownership team, global patents, and a small float that should lead to huge returns. Upcoming NOA and PDFUA catalysts within the next 30-90 days.
I have tax lien invested in Baltimore, MD. I actually won 3 liens in my first auction. This was years ago. I learned by doing research and reaching out to people who were doing it. Ned the owner of crabpropertiesllc. was willing to give me some advice and even connected me to the lawyer he used. Way more valuable than any course. If you want to learn biggerpockets is a great place. Also local realestate investment associations (RIA). In Baltimore, if the property is deemed vacant, you can start foreclosure immediately. All the properties were redeemed. One property was redeemed after I started foreclosure. In Baltimore, there is a pretty good system where you register your attorney if you start the foreclosure process. By doing so, the city ensures your attorney fees are calculated and paid upon redemption, along with interest. Most people bid and hope for redemption. I transitioned into rehabbing properties that were a better fit for me, but I am now looking to invest in tax liens again because I live abroad, and remote flipping is impossible. People say tax lien investing is sleezy. It isn't, the city provides a service, trash pick up, policing, schools, parks, etc., that residents agree to pay for by living in the city. When people don't pay taxes, the city's only way to enforce is to auction off the property. The investor loans the municipality money. And for the loan, the investor is given a small interest payment. Alternatively, if the city cannot raise money via taxes, it will have to sell bonds, thus raising everyone's taxes to pay back. If people aren't paying taxes, selling bonds to make up for short falls a vicious feedback loop. Lastly, many properties that don't redeem are usually vacant, public nuisances that cause blight to an area. Tax lien investors generally sell to property rehabbers, who take a property that would not qualify for financing and get it up to standards that a family can finance.
TACO approaching Dunkirk, MD, probably another 30 min in the air says TheAirTraffic
Bull spotted at local circle k buying MD 20/20 and kratom pills
thats cuz daddy upstairs (MD) cant actually write what they think, there is zero chance oil goes to 70 by eoy
Lots of MD promising therapies in clinical trials right now that will be game changers for the disease… don’t worry you’ll still be able to work if you hold through this upcoming crash
Once you’re diagnosed with a serious illness you are uninsurable. Nobody will sell any kind of life insurance to someone with MD.
Counter-analysis: 1. **THE CASH IS IN THE BANK (AND YOUR SHARES ARE DILUTED).** The $10.5M was raised via a PIPE involving Series A preferred stock and blocks of Series B and C warrants. Raising $10.5M on a sub-$5M market cap severely dilutes the retail float. The touted "extra $20M" arrives only if warrants are exercised, creating a permanent ceiling of selling pressure (warrant overhang) that caps upward momentum. 2. **CEO IS PUTTING HIS MONEY WHERE THE INSTITUTIONS TOLD HIM TO.** In micro-cap rescue financings, a CEO buy-in is rarely a voluntary show of confidence. It is a structural requirement demanded by institutional investors. If insiders refuse to put capital at risk, the institutions walk and the deal dies. 3. **MD ANDERSON "PARTNERSHIP" IS A VENDOR CONTRACT.** This is semantic spin. MD Anderson was added in February 2026 as a clinical trial site, not a commercial partner. Biotech companies pay hospitals to run trials. It is a paid vendor relationship, not a medical endorsement. 4. **THE JUNE CATALYST IS A PHASE 1 TRAP.** The mid-2026 data for ATR-04 and ATR-12 comes from early-stage trials designed to prove safety and dosing, not efficacy. Even with positive data, Azitra is years and tens of millions of dollars away from FDA approval. This guarantees future massive dilution to fund Phase 3. 5. **THE COSMETIC SLEEPER IS A DESPERATE PIVOT.** Launching a cosmetic program immediately after a distressed financing is a standard micro-cap distraction. It generates retail hype and promises near-term revenue while cash-burning clinical trials face long regulatory timelines in the background. **The Play:** The volume is surging because warrants are being prepped to dump. The bottom is not in at $0.24. We are consolidating for the next leg down. Analysts have targets at **$2.00+** to create exit liquidity for the institutions, and retail is walking right into the trap.
let me bring another one brtx : start with the ugly: just put out 10-k, real ugly as expected, just some from: At current burn rate, it has approximately 3.3 MONTHS of operating cash remaining without new capital. Even reducing burn by 30%, runway extends to only \~5 months. The company MUST raise capital before June/July 2026 to maintain operations. 10-K MD&A specifically notes 'possible second period + reverse split' as compliance paths. Management is explicitly signalling that a reverse split is being considered as a compliance mechanism. Historical context: BRTX has executed 4 prior reverse splits. The question is not WHETHER a reverse split occurs — it is WHEN and at what ratio. moreover, $3.326M in stock-based compensation was recognized in FY2025. For a company with $359,700 in total revenue, stock-based comp represents 925% of annual revenue. This is structurally standard for clinical-stage biotechs, but means management is compensating itself substantially with equity at prices that are continuously declining. At $0.29/share, the options and restricted stock granted to management have questionable retention value — many prior grants are likely deeply underwater. and there are some more, you gotta look up...! but tomorrow, at ORS Conference, Francisco Silva will present \~45-patient blinded interim (largest dataset yet) - Phase 2 Blinded Data. you gotta dep dive into management team (and more). reason i brought this up is because the man, Silva, is a genuine stem cell pioneer — Section Editor of the Journal of Translational Medicine, original discoverer of the BADSC 3D aggregate, co-inventor of the hypoxic culturing protocol that gives BRTX-100 its disc-environment survival advantage. check it out. check also ceo Lance Alstodt and the others. obvioulsy there are some possible scenarios for ORS data, bear/neutral/base/bull. check it out and take care! https://firstwordpharma.com/story/7142778#:\~:text=Francisco%20Silva%2C%20BioRestorative's%20Vice%20President,Chief%20Executive%20Officer%2C%20and%20Chairman.
Except the analogy would be if MD kept dangling a few fries for you as you got up.
I wouldn't put much stake in any of the crap you said. I work in the industry. Everyone is required to have testing, everyone is required to put the lab work on the label ot some extent. in my state they have QR codes so you can actually read the entire lab work. "Safe, clean cannabis." is as worthless a statement as "Cage free chicken," "cage free eggs," "humanely farmed," or even "Kraft Real Cheese." There is a lot of "Certified" this and that that does not mean anything besides that they paid a fee to some organization that then let them use such logo. Here's a worthless Cannabis statement for you, "Safe, clean Cannabis, organically grown in the USA, 3rd party tested, voted favorite strain of "yadda yadda," packaged in environmentally friendly packaging." I could go on but I think you get it. Then again they put dumb shit like this on products because people think they mean something, when in fact they don't. Like "Kraft Real Cheese" is in fact not "real" cheese, its "Real Cheese." Anyways we all have to follow pretty strict regulations in most states. You will know if a company isn't good because they will have regulatory violations or recalls. There was a company in MD called Forward Grow that was forced by the state to sell their license for using unapproved pesticides. So things do happen and people do get punished sometimes.
In Accident, MD we've switched over to home made gas
Again because: Absence of SEC filings not the main issue. If you read the whole report then you can see the narrative vs reality. "**The narrative pushed to retail investors** (via HydroGraph's website, investor deck, GlobeNewswire PRs, LinkedIn/X updates, conferences, and retail forums) is classic "graphene moonshot" hype: * **"Leading commercial manufacturer"** of the purest (99.8%) graphene using revolutionary, eco-friendly detonation tech (Hyperion system) "unlocking the promise of graphene for the world," "highest quality at greatest cost efficiency," "industry first" for consistent batches at scale. * **Regulatory wins = immediate market unlock**: US EPA TSCA approval + UK/EU REACH clearances (announced Feb 24, 2026) mean "commercial scale graphene sales" are now possible across North America/Europe; "three key milestones that meaningfully expand our commercial markets." * **Scaling explosion**: New Austin, TX headquarters + second production facility (LOI with major industrial gas supplier); building more reactors; "centralized production" targeting "hundreds of tons" capacity; low-capex model could deliver "$100M+ sales" from $10-15M investment. Texas = "central hub" for US ops. * **Customer/revenue ramp**: 60+ active customer programs (auto, defense, composites, lubricants, concrete, etc.); "larger purchase orders and long-term supply agreements" imminent; "first contracts expected"; partnerships (GEIC Tier 1, Hubron, etc.) will drive explosive growth in 2026. * **Financing validation**: Recent C$30M LIFE offering closed March 5, 2026 (at C$5.10/unit) proves strong demand and funds the "Texas scale-up." Market cap run-up reflects "year of transition" to profitability. Retail sentiment (forums, X) often amplifies this into "DoD/defense plays," "revenue explosion 2026," and "superior to competitors." **The reality from official filings** (latest SEDAR+ MD&A for FY ended Sept 30, 2025 dated Jan 27, 2026 + Q1 ended Dec 31, 2025 filed March 2026; financial statements; OTC uploads): * **Revenue**: Still negligible. FY2025 total sales = **$43,051** (up from $6k prior year). Q1 FY2026 = **$19,685** (mostly small research quantities/services). Inventory produced to date: \~500 kg. No major/long-term contracts or meaningful product revenue. * **Losses & cash burn**: FY2025 net loss = **$8.15M** (worse than prior $5.3M). Q1 loss = **$3.15M**. Operating cash outflow: \~$4.8M (FY) / $2.5M (Q1). Accumulated deficit now **$26.5M**. Never generated profit or positive cash flow from operations. * **Production status**: One operational Hyperion reactor (10 tonnes/year theoretical capacity) in Kansas since 2023. Two additional reactors under construction (Jan 2026) for validation before possible Texas move. Texas "production facility" = early LOI + Austin HQ lease/leasehold improvements only **no commercial output yet**. All inventory costs are expensed (no capitalization). * **Dilution**: Shares outstanding exploded to **\~340–347 million** (weighted average 333M in Q1). FY2025 + subsequent: multiple private placements, warrant/option exercises, and the recent C$30M raise (adding \~5.88M new shares + warrants). Heavy ongoing dilution to fund burn. * **Liquidity & risks**: Explicit "material uncertainty related to going concern" in every MD&A. Survival depends on continued equity raises; "no assurance" of funding or commercial success. Risks include scaling execution, market adoption, competition, regulatory conditions, and need for more capital. * **Outlook language**: "Expect" larger orders "within calendar 2025" (didn't materialize at scale); "targeting" Texas expansion; clearances "enable" pursuit of agreements but cautious, no quantified revenue guidance or timelines for profitability. **Bottom line, the gap**: The retail story sells **"we are a commercial graphene producer scaling now with regulatory green lights and big contracts coming"** (positioning it as ready for multi-billion markets). The filings paint tiny sales, accelerating losses, heavy dilution, and all future growth still "expected" and fully dependent on perfect execution + more raises.
Start your carreer working in goldman sachs at age 21-22 and be born into a well connected family, your father is friends with the CEO of the margin call hedge fund that will make you MD by age 32
I highly doubt they set up there AI correctly for me right now Claude is doing fine managing 14 db bases in my app. It has a total of 11 agents and fees into one another to keep pushing updates while also updating its own MD files and using git to see changes. All changes start with a new context window that allows further changes and development. I think i use around 1600-2000 context right away but runs smooth enough.
For clarification I'm an MD who works for a biopharma in clinical development and I don't regard the data as promising. I would suggest that I'm a better person than the one who is trying to convince gullible redditors to gamble their life savings on a lottery ticket biotech
MD Radiologist here. I can just say that all radiologists journals are full with articles about ai usage. For the last 5 years. I did not dig into this company but imo there is no moat. There are many others doing this, most are private. And by the way 10800 brain scans is nothing, it is 1 small Hospital with a Neurologe emergency / stroke department. Maybe they execute better than all others idk
You should read at least the most recent 10-K, but 'reading a 10-K' doesn't mean reading every word. There's a lot of boilerplate (most of the risk factors and notes are usually skippable if not doing a deep dive). I'd focus on the business overview, MD&A, and financial statements.
your an MD, you'll get a return on your investment in 40 years. They punish us investors so that the medical class can slave away all their life and think its normal.
Honestly, I don’t read full 10-Ks unless it’s a large position. I usually look at summary financials, earnings presentations, and maybe the MD&A section. Full reports are dense and time-consuming, so I focus on the key metrics that matter for that sector.
I don’t read every line unless I’m seriously considering a position. Usually I skim the 10-K first. Business overview, risk factors, cash flow statement, and then I’ll dig into the notes if something looks off. The MD&A section is actually more useful than people think. Quarterlies I treat more as updates than deep dives. There’s definitely a learning curve, especially across sectors. But after a few reads you start recognizing the patterns and what actually matters vs filler. If I’m just buying broad ETFs though, I don’t bother.
Not a fan of the man, but this idea isn't entirely garbage. I think some version of Universal Basic Equity can be a part of the solution to the growing income inequality and future disruption. Won't replace $100k annual salary, and coming up with $1k to deposit to get the match is a trick if you're unemployed, homeless and hungry. Doesn't help the worst affected. Should be universal like the baby trump accounts. UBI - Universal Basic Income - widespread acceptance that this will probably be necessary UBE - Universal Basic Equity - most people never heard of it, but it makes sense that if machines are taking over the entire economy that the people should have at least part ownership in the means of production UBS - Universal Basic Services - This is probably the most important. The LLM's are already providing a near universal service in free chat and analysis. The most obvious place where this can have a massive impact is medical care. With a few peripherals, a $10k superintelligent robot will be able to diagnose and treat illness better than a human MD, lowering the cost of doctors visits close to zero, excepting things requiring advanced testing equipment. They could do dental work, too. They can do nursing work and wash dishes, and do laundry. yada, yada. Mostly just the cost of electricity.
I’m lacking like 14 points in BMI but I do have an MD does that count?
You can use your own rhetorical "many trials have failed and therefore this is destined for failure" for any therapy being developed. Historical failure rates raise the bar, but they don't determine the outcome of a mechanistically unique therapy with a demonstrated CNS pathway correction. Here we have a genetically validated pathway (GBA1), plus strong evidence of Gcase dysfunction and corresponding lysosomal lipid accumulation in a good portion of idiopathic cases. If you are an MD, you should understand the relevance of GBA1 PD and Gaucher's-- they share the same GBA1 mutation. Life-saving, disease-modification was achieved by addressing dysfunctional Gcase, with GluSph being the most important biomarker for confirmation of target-engagement and disease progression. Of course, these Gaucher's therapies do not cross the blood-brain barrier. GT-02287 addresses dysfunctional Gcase in the brain. The reasonable take would be, "let's see how reducing GluSph levels translates to reduction in downstream biomarkers and in clinical symptoms in Parkinson's cases over a longer timeframe." Not, "I'll eat my shoes if this works". Hard to take you seriously when you are so seemingly dismissive without offering mechanistic reasoning to back up your statements. It almost seems as if you want it to fail. Do you work for a competitor of Gain? That would explain it. "Your post history is rabid with support of this stock... you are looking for someone to buy your bags." This is an immature, ad hominem assumption that does not address the science. Yes, I believe strongly in this treatment. I think it is the most promising PD treatment being developed, for the reasons I've detailed in my many posts. I'm lucky to have a very low basis. I *am* looking for BP to buy my shares for multiples above by basis. Not retail investors. I won't convince you-- not trying to convince you. But readers should understand that your baseless dismissal has no bearing on what many experts think is a very promising development in Parkinson's disease treatment. Maybe we should follow-up in September and see how durable the data is with the 16 out of 19 patients who elected to continue with the treatment despite the tests and additional lumbar puncture, many of whom have reported improvements, along with their clinicians. Beyond UPDRS, some of these reports may be anecdotal, but if they truly have regained sense of smell, this does not happen with placebo.
The inverse Micheal Beary MD, the Michael Bully if you will
I am an MD who works in clinical development for a biopharma. I've seen trials with much better clinical validation of the target go belly up.You are reaching heavily. I am not denying that this drug reduces GluSph, but I will eat my shoes if this leads to clinically meaningful changes in prespecified clinical endpoints in a phase 2 or 3 trial. Your post history is absolutely rabid with your support of this stock. You are looking for someone to buy your bags. If this drug goes to a large phase 2, I will probably short it before readout because I know how this ends.
TMDX just popped on latest earnings — I invite you all to evaluate this company. The product is basically a circulatory system for organs procured for transplant. That may not seem important but what that does is GREATLY increase the time one has to move and transplant an organ, thereby vastly increasing the availability and viability of already scarce organs. They just got an Investigational Device Excemption for hearts, which will add on to their already FDA approved devices for Lung and Liver. And they have best earnings four quarters in a row. They just expanded their office space. Why I think this is a very good long term play is: 1) the diseases served by transplant are from diseases of vice (smoking, drinking, uncontrolled diabetes), which will never truly be conquered non-surgically because treatment requires patient compliance. 2) immunomodulating therapies are moving closer and closer to safely creating universal organs. We are years away but the point is this is revolutionary science and I believe transplanting organs for longevity is going to be a very real thing in 20 years. Fair warning: I’m a retard MD and we notoriously make bad investment decisions. This one has been paying off well. This isn’t financial advice, just something that’s actually in use that is showing up in more and more hospitals.
iBRX straight growth ahead with growing approvals pulse now having trial at MD Anderson,European trials100% VOO should have pullback soon.
12,500 AML CR2 / CR3 Patients who'll be Eligible each year + 40,000 AML CR1 patients, each new year -to add to the 100,000 patients currently in remission who will immediately be eligible and benefit from Gps Immunotherapy. and if you think the FDA isn't going to approve Gps Condiditonally for CR1, after seeing 4x Increase in survival to 24-30 months for Cr2 with NO SIDE EFFECTs, near 100% Quality of Life, combined with the MSKCC Phase 2 CR1 TRIAL DATA of 67.6 month MOS - Better than Transplant, if you think the FDA is going to wait 5 years for a trial, when the Chair of MD ANDERSON's Leukemia Dept., running the Global P3 requested Expanded Access to GPS for CR1 patients, and they also submit that EAP DATA. you have more research to do u/Away-Information9841
iBRX. PLSE you are welcome the story- IBRX will treat Lymphopenia Comman problem on cancer therapies. approved now in UAE, EU next for bladder cancers. outstanding results in small groups with glioblastoma pLSE new treatment for atrial fib. 100% success, 96% at one tear. Procedure 1x 6-8 min. just started clinical trial at MD Anderson. very early stories. IBRX will make millionaires but more important save lives . Already has a safety profile and case reports
Lmao yeah he turned into MD orange coat quickly
MD isn't so bad and you should be able to deduct half your SPAXX growth from your state income. The killers are CA, NY and CT where if you don't meet a threshold you deduct nothing.
Spanberger is now (just got into office) going to require data center owners/operators to front “all” their energy costs. At least that’s the plan, but she’s one of a few leader coming out saying that. Not even MD’s gov has the nerve to do that…
An MD that makes money? Craziest year yet.
The recent GradPlus loan changes have capped total loans at $200k for professional programs (like MD). This means fewer people can become doctors. The recent GradPlus loan changes have capped total loans at $100k for non-professional programs (like CRNA, NP, and PA). This menas fewer people can become the people that reduce doctor workload. Our future: * Fewer doctors * Fewer advanced healthcare pros who reduce doctor workload If the loan limits aren't fixed ASAP, this is going to have devastating effects on healthcare.
A federal bill designed to block marijuana businesses from claiming standard tax deductions even if marijuana is rescheduled has gained its 15th sponsor in the House and Senate, and its second new sponsor this week. House (HB 1447) * Jodey Arrington (R-TX) * Vern Buchanan (R-FL) * Blake Moore (R-UT) * Gregory Murphy (R-NC) * Adrian Smith (R-NE) * Nathaniel Moran (R-TX) * Charles Edwards (R-NC) * Gary Palmer (R-AL) * Pete Sessions (R-TX) * Andy Harris (R-MD) * Andrew Clyde (R-GA) * Michael Lawler (R-NY) Senate (S. 471) * James Lankford (R-OK) * Pete Ricketts (R-NE) * Ted Budd (R-NC) * per MM
These days, the boards are filled with these healthcare jobs requiring a MD or DO along with board certification that pay only $190k
Hello. James Mason, MD at Philedelphia Logistics, but you may know me as u/BumsRFunny5797, moderator on r/butt_plugs
#TLDR --- Ticker: HIMS Direction: Up Prognosis: Long Shares & LEAPS for March 2026 Credentials: "Regarded MD" Secret Weapon: Liposomal delivery (bypasses Big Pharma patents) Strategy: OP argues Hims is playing 4D chess. The recent product "pull" was a publicity stunt. Hims is partnering with Strive Pharmacy to use liposomal technology, which bypasses Novo Nordisk's delivery patents. With a major GLP-1 patent expiring in March 2026, Hims is positioning to legally flood the market with generics while using the current price crash to execute cheap buybacks.