PFE

_foundation

That Metsera acquisition was so Bourla. Can’t stomach spending real money for real pipelines so PFE will continue to wallow in mediocrity. Obesity is the hottest TAM imaginable in biotech and they blew it as usual.

Total-Distance-6700

Do they have anything promising in their R&D pipeline or do those funds all go to dividend payouts? If you want robust upside price action then PFE needs a new blockbuster drug.

Remarkable-Drive3503

Christ, I just looked at PFE. So glad I got out of that shit stock on the last pump. It completely DIED AGAIN! Fuck that shit, wasted a whole YEAR there sucking on shit divs.

MoneyForNothin16

PLUG, HOOD, OPEN, HIMS, PFE all recently had days on comparable good news the run kept going the entire day

salty0waldo

I honestly do not know what to make of PFE and BMY anymore. It just seems that both of these pharma companies cannot gain any positive momentum? I understand both pipelines are in question but PFE has had a ton of M&A with BMY having one of the strongest late-stage pipelines. It just seem very odd that they continue to sell-off on really, any news.

No-Improvement3164

PFE created new bag holders. 😂

CrestCrentist

Expect a good rebound day with PFE. Still phenomenal value for exponential growth

Mindless-Bug-8397

So OPEN AI a company with revenue of $5B in 2025 has announced $1T in deals and more to come. Awesome, mostly people are using Claude for development and Gemini for business. Open AI market share is shrinking. I hope to see the bubble burst in the next 6 months. Long Google PayPal NBIS PFE

Odd_Papaya8305

Is PFE cooked?

Fun_Illustrator9298

I’m glad I’m not the only one. 25 $16c @ $1.60 average. It appears to hit bottom late last week and is moving on up. Trump always trashes something and then gets a bribe to be best buddies. See intel and LBT. Tim apple. Etc. trump has something cooking here. PFE style is my guess.

PowerDreamer2493

I thought PFE was getting the federal pump??? My calls???

rocier

That PFE guy said my bags would be lighter! he lied!!

skilliard7

>Additionally, it's not fair to compare say the SPY with these foreign equities. Most of the equity inflow into America is into stocks like the mag7 as opposed to general indexes. Which I think draws attention to something, which is the fact that many non-tech companies are trading at extremely cheap valuations. Conagra brands, General mills, Kraft Heinz are all trading at <10x normalized earnings, as consumer staples stocks that are generally recession resistant. PFE is trading at 13.5x earnings as healthcare. Comcast is at <8x earnings(not counting 1-time profit from Hulu deal), VZ <10x earnings, T at 15x earnings in telecommunications. REITs are very cheap as well, with many below the estimated NAV of their underlying holdings. I don't think we are in an "everything but cash" bubble. Yes, there are many alternative assets like precious metals and crypto which have been skyrocketing. But I think it would better be described as a "greed" bubble. People want to own assets they think can double in price 1-3 years, not boring stable companies that grow earnings at 2-4% a year and pay a 7% dividend.

Sidney1973

Brother, the option action is real. They will revive. https://preview.redd.it/2j8aa31n1xtf1.jpeg?width=1290&format=pjpg&auto=webp&s=2eaccc8217bd89e6a8fa24876d2de8d93964c44a Pfizers shift a $7.3 billion bet on metabolic breakthrough. Summary of Pfizer’s (PFE) recent activities and market perception, focusing primarily on their maneuver into the weight-loss drug arena and government-related commitments. The Acquisition and clinical edge I. Corporate Development Strategic Move: Pfizer executed the acquisition of the biotech firm Metsera, Inc. Valuation: The purchase was structured with an initial value of approximately $4.9 billion. The total transaction value could reach up to $7.3 billion, contingent upon Metsera's pipeline hitting specific clinical and regulatory milestones. Market Rationale: This move represents Pfizer's re-entry into the obesity/cardiometabolic drug sector, aiming to secure a significant growth for the late 2025 and into the 2030s. II. The Next-Gen Clinical Pipeline Metsera's assets are designed to solve two problems of current weight-loss injections: frequent dosing and side effects. Lead Injectable: MET-097i (GLP-1 RA) Status: Rapidly advancing toward Phase 3 trials (initiation expected in late 2025). Differentiation: The drug is engineered for once a month injection, providing a major convenience advantage over existing weekly therapies (e.g., Wegovy/Zepbound). Efficacy Data: Mid-stage (Phase 2b) results showed mean placebo-subtracted weight loss of up to 14.1% at 28 weeks, with strong indications of better tolerability compared to competitors. Combination Therapy Backbone: MET-233i (Amylin Analog): This is a non-GLP-1 drug also positioned for monthly dosing. It recently delivered positive Phase 1 data. Combination Goal: The key asset is the prospective single, once-monthly injection combining MET-097i and MET-233i, intended to achieve greater efficacy than monotherapies. Clinical data for this combination is anticipated in late 2025/early 2026. Revenue Projection: Analysts project that the total Metsera portfolio could generate over $5 billion over the next five years, once fully launched (likely late 2020s/early 2030s). III. Patient retention focus. The Industry Problem: Real-world data shows poor patient retention on current weekly GLP-1 drugs, with only 8% to 14% of users remaining on therapy after three years. When patients stop, they regain the weight. Metsera's Solution: By moving to a once-monthly schedule and demonstrating tolerability (fewer G.I. side effects), the Metsera portfolio is positioned to increase long-term patient retention, thereby maximizing the clinical and financial value of the therapy. PAGE 2: Pricing, public policy, and valuation. IV. The Public Policy and Investment Commitment The $70 Billion Pledge: Pfizer publicly committed to channeling an additional $70 billion into U.S. research, development, and domestic capital projects over the next years. The Quid Pro Quo: This investment commitment was made as part of a voluntary agreement with the U.S. government on drug pricing. In exchange, Pfizer secured a crucial three-year exemption from potential new pharmaceutical tariffs and regulatory stability. Pricing Impact: The agreement included lowering costs for Medicaid patients ("Most-Favored-Nation" pricing) and offering select drugs at heavy discounts (up to 85% off list price) through a planned direct-to-consumer website. This move provides certainty by aligning U.S. pricing with other developed countries for newly launched drugs. V. GLP-1 Pricing Structure High Cost Drivers: The cost of GLP-1 drugs (list price of $500 to $1,400 per month) is primarily due to: The absence of government price negotiation in the U.S. Monopoly pricing enabled by patent protection (lack of generic competition). Pricing based on the lifetime value of treating obesity and preventing major cardiovascular events. Metsera Pricing Outlook: While Metsera's drugs have no official price yet, the single monthly dose is likely to be launched with: A high list price (likely $1000 to $1500/month) to maximize revenue from insurers. A deeply discounted self-pay price (likely $499 to $800/month) to compete directly with existing self-pay programs. VI. Market Valuation (PFE Stock) Recent Stock Movement: Pfizer's stock price recently surged (up 6.83% on Oct 1, 2025) following the dual news of the Metsera deal and the government pricing agreement. This reaction indicates the market views the long-term strategic moves as a significant positive. 12-Month Price Forecast: The analyst consensus for Pfizer's (PFE) 12-month target price currently ranges from $29.71 to $36.06. The overall average rating remains Hold but with a bullish skew, factoring in the Metsera pipeline success. Options Market Signal (Jan 2028): Trading in long-dated call options shows market interest centered around a $35 strike price, suggesting that investors view a price of $30 by early 2026 as an achievable success scenario given the potential of the new obesity and cancer portfolio.

ai-moderator

#TLDR --- Ticker: PFE Direction: Up Prognosis: Buying 10/10 $26.50 Calls because vaccine approvals, cancer drug wins, and a new weight-loss pill acquisition will make the stock great again. Bonus DD: The Cowboys and their fans are 🤮

Intelligent-Shape888

the issue with PFAS has obviously been weighing on the stock but you could be onto something. maybe a possibility for a PFE-like deal at some point for these types of companies? i'm into this from the data center cooling angle but results have been mixed at best.

Playa4thee1

Bro, I have several options for PFE. But my strike prices are $29.00 and $30. This stock does not move that way unless something unforeseen happens. Remember, you only pick stocks to go above 50% if they are already on a bull run or if it is a hot meme stock.

DeepestWinterBlue

So glad I bought NVO over PFE

Electrical-Order1317

Yep I bought Nestle, KVUE (after Trump shot off his mouth about Tylenol lol) and some other beaten down stocks because these will keep giving me dividends and will last during a recession. Certain things like UNH are undervalued and PFE and NVO. The only stock of mine that I wish would take off his BYDDY (BYD) it still has time and it has taken over Tesla in sales in Europe. Eventually they WILL be sold here just not in this administration

Electrical-Order1317

I’ve reallocated some into stocks like KVUE, UNH, PFE, NSRGY because they are so beaten down. Even when shit hits the fan people are going to buy Tylenol (lots of it for their headaches) lol and other personal care items and food.

shmoopdoop6969

Why PFE

PaperHandsTheDip

might be the trade. I've heard a lot of PFE whispers recently

Mindless-Bug-8397

Wakeup Sell all Buy 20000 shares of PFE Go in coma for 6 months Buy back SPY at 450

Mindless-Bug-8397

NVDA indirectly buying own chips to pump revenue. Peak bubble. Transitioning all to INTC PFE and other govt backed companies

MannieOKelly

Well, assuming you have earned income make sure you're putting the max $$ into that ETF in a Roth account. Also I haven't done the math but I wonder what your AI friend was assuming about your preference for income vs growth. If you put $1,500 \* 12 = $18K/year into an SP500 ETF for 12 years, you'd likely have at least $250K by the end. Then if you switched it into high-yielding stocks like T or PFE (or a high-yield ETF maybe) you would be generating over $12K/year of dividend, and the part of that that was from the Roth would be tax-free. That said, your goal is probably not well-considered, and the above calcs assume that SP500 returns and inflation don't change much.

Financial_Lie7354

PFE calls NVO calls NVIDIA calls TSM calls AMZN calls. Bull 4 life

Financial_Lie7354

Is PFE too regarded or next pump. Please help me gamble

Simple-Locksmith3447

$PFE has one good week in an year and cliff dives every other day. Such piece of shit stock to own

Odd_Papaya8305

Does PFE Pfizer have a chance of climbing up even more?

rocier

stupid PFE guy said my bags would be free...

Bagholder147

PFE $30. Tyson $49.

dbchocochip

Use your last $9 to buy PFE $36 calls

Bagholder147

PFE $30

Embarrassed-Sea-6078

I would try really hard to avoid biomedical stocks like IXHL, SHOT, FEMY, or RVPH. Or you would have to be very diligent and proactive in getting out as well as you can when you are at the top. Biomedical stocks usually drop very fast whenever something positive happens as everyone wants to “buy the rumor, sell on the news”, so usually there’s not very stable long term gains on biomedical stocks aside from the big names like NVO or LLY or PFE. Quite a few of us have learned the lesson the hard way with things like OTLK or MBOT or FBIO. Once the catalyst happens, biomedical stocks usually drop and takes a long time to recover again since it takes a lot of effort and capital for a biomedical stock to actually advertise and produce the said development

Maleficent_Ad_3070

Buy PFE that is all. Enjoy the weekend you highly regarded individuals.

MaultyH

Moderna (MRNA) and Pfizer (PFE) had a great week. I have been long on both for a few years now, but lately Moderna has been underperforming and can’t seem to break the trend; it predictably drops below $25 when nearing $30, despite the prospects being good, zero debt, and having new FDA approvals for more than just COVID-related vaccines. If they meet their mark this year, a fair valuation can easily land MRNA between $35 and $55; some analysts even say $80 isn't unreasonable. Considering how the anti-science party and anti-vaxers dominate the government, it's understandable to be conservative, naturally, with buying into biopharma and immunization tech right now. However, given how these stocks performed through the imminent government shutdown, I can't seem to make a reasonable bear case because factors such as the lack of government funding and FDA regulations cannot seem to compromise their growth seriously; in fact, it seems to stimulate it.

Beginning-Medium6934

They didn't triple. But PFE 25 and 27 Sep26 calls.

PaperHandsTheDip

Could be related to the US / PFE deal

Thisispaartaaa

There goes PFE again...$42 inbound eoy?

Wide_Neighborhood_49

My $25 PFE puts will indeed expire worthless today. Yay! More tax write offs I guess

pp363

PFE with this PE is CRIME. I wish all we can win.

Professional_Help_85

PFE most likely will buyout CRBU as well stepping into CRISPR space

Skanlez

GL. I did one this week $100 to $1000 and hit it with one play. Bought PFE 21.5c @.11 for 10/10 and sold at 1.50 holding 10 contracts

yes2matt

Ok, does your platform give you data on Open Interest? You were right in your expectation that PFE would go up significantly, but you bought so far out that 1. the two dollar bump didn't matter; and 2. there was no market/liquidity at that strike/date. It is just me, but if I'm intending to swing trade, I think, "what is the maximum time I'm willing to hold?" and then I double that time for the expiration date. So like to your example if I was thinking a 30-60 day hold, I would be buying 80-100 DTE.

Crazy_Donkies

Zero.  Not in this environment.  I'll use margin for quick moves I believe will pop.  Just used it for PFE, DELL, and RZLV calls.  Made a quick 50%, sold them, set aside $ for the IRS, paid off margin, and on to the next thing.

partypantsdiscorock

I don't trust tech right now. Yeah, it's hot, but too hot imo. I am mostly in pharma stocks right now because it was the main sector I saw as undervalued. My largest holding is PFE, and I bought more as soon as I heard about the new pricing agreement. They have done a great job on building their pipeline back after the covid success and subsequent drop in sales/price. They consistently meet their sales and savings goals and the CEO has said he is committed to maintaining the dividend (the dividend has increased annually since 2009). My dividend yield on cost is 7% and my timeline is 10+ years, so while there's volatility in tech I see it as a savings safe-haven (collect on the dividend until things stabilize elsewhere).

CrestCrentist

PFE held it’s own today. Expect a big rip tomorrow

jarMburger

Take a nap and sell some puts on PFE.

Same-Brilliant2014

My commie port: INTC, Fannie and Freddie, LAC, MP, PFE. Who else is either owned by US or getting special treatment? 🤔

version-two

PFE just dancing.. consolidating. Maybe? $27 resistance

DurianWaste2724

I also bought PFE today.

toxicomano

It has to get there today for the 100k too. I wish OP good luck, but as someone who held PFE for 10 years (2008-2018) I feel like I know the ending here.

Guacamole54321

Nice. I just bought PFE.

CLYDEFR000G

Woooo best of luck to you! I’m also long on PFE

CrestCrentist

Pfizer! PFE to the 🌕

JR_Soup

pharma deal + govt shutdown = PFE???

TotallyNotCIA_Ops

Sorry OP but PFE hasn’t been at $34 since Sept 2023, and it’s dropped about 20% since then. Right now it’s at $27, so for your calls to even be in the money by March **the stock has to climb back to $34, sothat’s about a 26% move up in 5 months** just to break even. So it’s not a glitch, it’s just that the options are way out of the money and the market’s basically saying it’s super unlikely PFE makes that big of a jump that fast.

Chemical_Hospital154

I hold PFE leaps and sold them 2 days ago after 3% jump. Thats nothing that it kept climbing another 10% these two days.

JustNotFatal

I buy when I see opportunity (and can act on it financially). I’m not a DCA’er. As long as the investment thesis has not changed, I don’t sell. I’ve had some incredibly successful swing trades that I regret selling ( META, Apple, AMD) On the flip side recognizing a bad or I misunderstood company and selling is vital too (UPS, ALB) I try to recognize undervalued companies. PFE was a recent buy that took flight way sooner than I anticipated

Odd_Papaya8305

Call on PFE tomorrow

db_10314

You must realize that at such an out-of-the money option, with only 19 in open interest, you bought your contracts from a market maker. They will happily sell you that contract no matter what the underlying stock price is. However the market maker is not obligated to buy them back from you when you are ready to sell. To my understanding, when you bought them at .19, shortly after, PFE dipped just enough to the point that the market maker didn't even want to buy back anyone's options at the $36 March/2026. They didn't even bid on the option spread so essentially there was a brief moment that there was no liquidity to exit your position and hence the value was .01. Once the price of PFE rose, the market maker began offering buy quotes. Lows for the day were .19 and high was .24 so at a very brief glace, you did not lose money on your trade and actually made some profit despite the mini heart attack you got seeing the value of your contracts at .01. Correct me if I'm wrong, still learning about options myself.

version-two

It’s not the tariffs. It’s the preferential treatment they’ll get. The inevitable win you’re handed when you get front run by the fed. And the cult forgetting how much they hate masking and vaccines cuz daddy cut a deal with them. They tend to go quiet pretty quick when the narrative changes. I believe part of their devaluation was tied to negative sentiment - when all them regards are screaming about autism and covid ruining their lives for 5 years, it can’t help the stock. Tomorrow it’ll be like the Epstein files - they’ll “forget” it happened. It’ll be the best and greatest deal. I’m long on PFE either way and up. But who knows, this is a casino, sir.

smoop86

Why? Tariffs paused. PFE should go back to 23

fightthefascists

Don’t worry bro I did the same exact thing today with LLY and…… PFIZER. I had like 275 PFE calls. 200 of them were a complete yolo play with 10/3 expiration. I made like $2000 sold and they went up another $15,000. Same thing with LLY I had 6 calls and sold them all too early.

version-two

More PFE, MRNA, and Merck. Calls. Patterns.

version-two

I’ve had this on a watchlist for 4 months. No news and 3x volume today… Unless someone has the scoop, I’m wondering if it’s being pulled up by the PFE jet stream. a lot of bio tech and healthcare seemed to move over the last 48 hours on the Pfizer news. $NTLA, $ABCL, $NUVB (yesterday), $MRNA, $NVAX, $MERCK… all up.

Better-Specialist479

Did you even look at a chart of PFE? For over a year it has traded in a range of around $22 to $30ish. What is going to drive a $10 move up? Acquisitions take 2-3 years to actual show up in stock prices. New drug development takes a decade. Nothing really coming online in near future. This is a 7% dividend payer great for DCA reinvestment of dividends for long term and maybe in 10 years it is up $10+.

version-two

You’re missing $PFE, at least short term. You’re more diversified than 75% of WSB though.

SpaceCatVII

Guise I'm finally profitable again after blowing up my account on MX and PFE

smoop86

Didn’t they pause the pharma tariffs earlier today? Now PFE is struck with selling cheaper drugs and having to set aside investments while others are still in pre tariff mode

bapachonz

I sold all mine today to buy biotech stocks like MRK and PFE. complete regard move but hoping for the best 🥲

Bagholder147

Took gains on PFE.

PlayerPlayer69

PFE $30 Strike, 01/16/2026. 150k+ Open Interest and 30k+ Volume. Weeks/Months leading up to that date has relatively very small volume and open interest. I don’t know what I’m doing, but it looks like *someone* knows *something*. I hope.

Crazy_Donkies

I agree, PFE, DELL, and NBIS is free money.

KingStoKing

PFE calls printing @ 100% already

reddituserzerosix

fuck i thought the PFE pump was over yesterday

version-two

I wanna punt 5k margin on more PFE lol… still holding positions above and added more.

BuyHighCryLat3r

Bought 10 PFE 26.5 calls yesterday for $0.04, sold for $0.13 and now they’re worth $0.94. if I were to hold it would have been flat I just know ot

BuyHighCryLat3r

I bought 10 PFE 26.5 calls yesterday for $40, and sold them this morning for $100, and they are now worth $850… It’s always when I sell. If I held them, shit would’ve been flat

A55BAG

Can someone do TA to PFE? should I sell?

miata_only

PFE? I hardly know her.

dkattir

Hoping for some advice! I own 100 shares of $PFE and had sold a covered call expiring this Friday 10/3 at $25.5 strike. How should I handle this based on everything that's going on with the stock right now? Roll over to another week for a .3-.4 delta? Just accept the loss and close the short position immediately? Or let it expire and face assignment? My personal opinion on PFE: looking at everything that's happening right now, the stock could rip up to $29 very fast. Anything beyond that is anybody's guess. I'd like to own the stock for dividends but don't mind getting assigned and buying the shares back later if that makes sense too. There's no ex dividend date around the corner.

NiceJobSon

Sold PFE for a pittance yesterday, hard to watch it going higher today.

Pojihut

PFE still going, $30?

The_Brand94

$PFE to $50 I don’t care how unrealistic it is, this market doesn’t make sense.

Mother-Chipmunk2778

Man really wish I bought those PFE calls yesterday just didn’t think it would rip for a 2nd day straight

FluorescentCheddar

I own 74000 share of PFE, AMA

XTradeOrDieX

PFE & LLY porn in production.

tachyonvelocity

Lol you guys are completely sleeping on biotech, PFE/MRK another huge gap up because tariffs are a nothingburger, but the point is biotech was literally having a big recession crash and became cheap as fck, even the servicers like TMO, WST, DHR, IQV, ICLR, BIO, TECH, AVTR all having 5% gap up days today.

VitaminStrange

I get it. We all had to start somewhere. I have a small LLC account with 500 k. 19k worth of calls in anything would be way beyond my risk tolerance, but that is me and I am very much so a big old pussy when it comes to risk/reward. I'm not trying to claim I "know" anything or that after three years as a "professional" I am somehow seasoned of grizzled. A thousand contracts $650 in fees alone at 65 cents a contract. That's a big fill. Maybe you have a pile of capital that 19k is a perfectly sized amount of risk for where you are at. I am under the assumption that this is not the case and could be wrong. Again, your instinct to buy PFE calls on the news was completely a logical assessment of the situation. It's your position sizing vs. your obvious and admitted lack of knowledge that I take umbrage with. The only way to really know this shit is to do it repeatedly for a long time. If you blow up the music stops and you start over from zero if you even come back to the market. Every day I learn something new, and every something new leads to at least two other concepts I know nothing about. I still don't know shit about shit but I am 100% that risk management is the most valuable lesson I have learned. The 19k says a lot of things, and one of them is that you truly have confidence in your ability to trade derivatives. If you didn't have that then you shouldn't be here at all. Compared to tens of thousands in potential loss the cost of buying books on the subject is minimal. If spending $150 on "Options Volatility and Pricing" is too high library cards are free. You are not fucked, but if you keep it up statistically you will be. Learning from your mistakes is key here. You have to fake it before you make it, bootstrap style. Many mistakes will be made, just don't let them bankrupt you. I'm rambling now, good luck with all that and maybe we will see you at tomorrow's opening bell.

A55BAG

Lol PFE is the next boomer stock. First ORCL then INTC now PFE. Boomers are always winning 🤣

2fingers

The bid/ask on options will go all over the place for a short period of time after the market opens. PFE has fairly tight spreads so it shouldn't be a problem to sell those 1000 contracts at any time without much slippage. It doesn't matter if there's any interest or not, the market maker will fill your close order.

VitaminStrange

The PFE trade is solid but getting very crowded. I think OP might dodge the steamroller on this one, but if OP is in the habit of LEAP then look its just a matter of time.

Siks10

Long time PFE holder and trader here. You already got good answers but let me add that those calls will definitely not print. PFE is not a meme stock although it sometimes swing wildly. Sell your calls at a profit well before expiry. Good luck!!

chancepack

PFE turning into a big money maker now being on the good side of orange man!!!

VitaminStrange

That's 19k worth of PFE calls. Looking at it now, you are ok, but I can't help but feel the fact you actually needed to ask this question might imply you are throwing way too much rope. You are trading a contract that expires in 170 days and is 22% OTM and wondering why the bid/ask is wonky in the opening hour? I'm not calling you out on the trade, but you are asking a $500 dollar question on a $19,000 position.

HanzDiamond

my PFE bags getting lighter. Thank you for your attention to this matter!

Realistic-Bottle-871

Fellow regards I have been given a 2% green pick yesterday (PFE). Time to get opinions on the next one. Is JNJ good for 2% scalp?

FluorescentCheddar

PFE vertical, there is a God

iMonterenfleche

PFE calls up